Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

Written By Lucia Morbidelli
Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
  • Publsiher : Academic Press
  • Release : 09 February 2019
  • ISBN : 0128172797
  • Pages : 372 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders written by Lucia Morbidelli which was release on 09 February 2019, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides readers with a clear overview of the recent findings and references as well as summaries, significant molecular pathways, and conclusions Discusses new ideas proposed and makes suggestions for further investigations that will advance the field Presents introductory and summary information on the contributions of the field, all the findings of the studies discussed, and projects future goals for research

Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
  • Author : Lucia Morbidelli,Benjamin Bonavida
  • Publisher : Academic Press
  • Release Date : 2019-02-09
  • Total pages : 372
  • ISBN : 0128172797
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Summary : Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various ...

Nitric Oxide NO and Cancer

Nitric Oxide  NO  and Cancer
  • Author : Benjamin Bonavida
  • Publisher : Springer
  • Release Date : 2012-09-05
  • Total pages : 250
  • ISBN : 0128172797
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Summary : Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the release of NO following treatment. NO has important ...

Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy

Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2022-01-14
  • Total pages : 294
  • ISBN : 0128172797
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Summary : Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormones, immunotherapies) are taken into consideration, along with advances made in combination therapies. The book ...

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
  • Author : Bharat B. Aggarwal,Young-Joon Surh,S. Shishodia
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-08-06
  • Total pages : 490
  • ISBN : 0128172797
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Summary : The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the ...

Nitric Oxide Donors

Nitric Oxide Donors
  • Author : Amedea Seabra
  • Publisher : Academic Press
  • Release Date : 2017-03-17
  • Total pages : 364
  • ISBN : 0128172797
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Summary : Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain ...

Inflammation in the Pathogenesis of Chronic Diseases

Inflammation in the Pathogenesis of Chronic Diseases
  • Author : Randall E. Harris
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-05-09
  • Total pages : 324
  • ISBN : 0128172797
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Summary : In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. The authors provide exciting and enlightening perspectives on COX-2 and related molecular targets in the future ...

Artemisinin and Nitric Oxide

Artemisinin and Nitric Oxide
  • Author : Qing-Ping Zeng
  • Publisher : Springer
  • Release Date : 2015-06-23
  • Total pages : 126
  • ISBN : 0128172797
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Summary : This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted “Molecule of the Year” by Science magazine, and the discovery of its physiological ...

Regulation of Inducible Nitric Oxide Synthase Expression in Human Cells

Regulation of Inducible Nitric Oxide Synthase Expression in Human Cells
  • Author : Martin Lee
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 127
  • ISBN : 0128172797
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Summary : Nitric oxide (NO) is a bioactive gas that has multiple roles in innate and adaptive immune responses and dysregulated expression of its production by inducible nitric oxide synthase (iNOS) is implicated in the pathogenesis of various inflammatory diseases and cancer. The mechanisms by which the expression of iNOS is regulated ...

Oxidative Stress Inflammation and Angiogenesis in the Metabolic Syndrome

Oxidative Stress  Inflammation and Angiogenesis in the Metabolic Syndrome
  • Author : Raquel Soares,Carla Costa
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-02-25
  • Total pages : 210
  • ISBN : 0128172797
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Summary : Metabolic Syndrome (MS) is a highly prevalent condition in developed countries and is a cluster of several risk factors for type 2 diabetes and cardiovascular disease that includes increased body mass index/waist circumference, visceral obesity, insulin resistance, hyperclycaemia, dyslipidaemia and hypertension, which are all major causes of morbidity and death. ...

Inducible Enzymes in the Inflammatory Response

Inducible Enzymes in the Inflammatory Response
  • Author : Willoughby,Tomlinson
  • Publisher : Springer
  • Release Date : 2013-03-11
  • Total pages : 214
  • ISBN : 0128172797
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Summary : This volume will be of great value to all those researchers in the area of the inflam matory response, notably academics, clinicians and members of the pharmaceutical industry. The book has in the main been restricted to three inducible enzymes, namely nitric oxide synthase (iNOS), cyclooxygenase (COX-2) and hemeoxygenase (HO-l), ...

Molecular Biochemical Aspects of Cancer

Molecular Biochemical Aspects of Cancer
  • Author : Undurti N. Das
  • Publisher : Springer Nature
  • Release Date : 2020-05-30
  • Total pages : 254
  • ISBN : 0128172797
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Summary : This book discusses the role of genes, oncogenes, anti-oncogenes, free radicals, PUFAs, anti-oxidants, lipid peroxidation process, telomere, and angiogenesis on the origin of cancer, cell proliferation, and cancer in general. It includes a broad introduction to cancer cells; genes, oncogenes, and anti-oncogenes; and free radicals. In later chapters, it discusses ...

Molecular Targets and Therapeutic Uses of Spices

Molecular Targets and Therapeutic Uses of Spices
  • Author : Bharat B. Aggarwal,Ajaikumar B. Kunnumakkara
  • Publisher : World Scientific
  • Release Date : 2009
  • Total pages : 430
  • ISBN : 0128172797
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Summary : Traditional uses of spices : an overview / Ajaikumar B. Kunnumakkara ... [et al.] -- Black pepper (Piper nigrum) and its bioactive compound, piperine / Krishnapura Srinivasan -- Cardamom (Elettaria cardamomum) and its active constituent, 1,8-cineole / Archana Sengupta and Shamee Bhattacharjee -- Molecular targets and health benefits of cinnamon / Kiran Panickar ... [et al.] -- ...

Inflammation

Inflammation
  • Author : Jean-Marc Cavaillon,Mervyn Singer
  • Publisher : John Wiley & Sons
  • Release Date : 2017-10-02
  • Total pages : 352
  • ISBN : 0128172797
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Summary : The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune ...

Melatonin

Melatonin
  • Author : Venkatramanujan Srinivasan,Gabriella Gobbi,Samuel D. Shillcutt,Sibel Suzen
  • Publisher : CRC Press
  • Release Date : 2014-10-15
  • Total pages : 573
  • ISBN : 0128172797
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Summary : There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics ...

Cumulated Index Medicus

Cumulated Index Medicus
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 212
  • ISBN : 0128172797
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Summary : Download or read online Cumulated Index Medicus written by , published by which was released on 1999. Get Cumulated Index Medicus Books now! Available in PDF, ePub and Kindle....