The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

Written By Rainer Straub
The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae
  • Publsiher : Academic Press
  • Release : 08 April 2015
  • ISBN : 0128033223
  • Pages : 390 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae written by Rainer Straub which was release on 08 April 2015, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting – cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation–related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging. Offers a broad conceptual framework with a strong clinical link, written in an easy to grasp style and demonstrating the link to aging research Describes the important principles derived from basic immunology that are used to explain pathogenesis of chronic inflammatory systemic diseases with a focus on autoimmunity Defines the bioenergetics and energy regulation of the body explaining common response pathways typical for systemic inflammation Makes use of evolutionary medicine theory to demonstrate the uniformity of the systemic response Explains the appearance of typical disease sequelae on the basis of the three pillars: neuroendocrine immunology, energy regulation, and evolutionary medicine theory Contains color figures and tables that explain the field to newcomers

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae
  • Author : Rainer Straub
  • Publisher : Academic Press
  • Release Date : 2015-04-08
  • Total pages : 390
  • ISBN : 0128033223
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Summary : Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, ...

Interventional Inflammatory Bowel Disease Endoscopic Management and Treatment of Complications

Interventional Inflammatory Bowel Disease  Endoscopic Management and Treatment of Complications
  • Author : Bo Shen
  • Publisher : Academic Press
  • Release Date : 2018-01-16
  • Total pages : 380
  • ISBN : 0128033223
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Summary : Interventional Inflammatory Bowel Diseases: Endoscopic Management and Treatment of Complications covers the preparation, principle, techniques, and damage control of complications in endoscopic therapy, providing the ultimate guidance in endoscopic management of IBD. With contributions from a panel of international leading experts in the field, perspectives are included from GI pathologists, ...

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  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-01-08
  • Total pages : 1808
  • ISBN : 0128033223
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Summary : Thoroughly revised and updated, the 7th Edition of Rheumatology remains a leading text in this fast-changing field, keeping you abreast of recent advances in medications, therapies, clinical trials, and much more. Dr. Mark Hochberg and his team of expert authors and editors cover everything you need to know -- from ...

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  • Publisher : Springer
  • Release Date : 2017-01-25
  • Total pages : 261
  • ISBN : 0128033223
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Summary : In three Volumes this mini book series presents current knowledge and new perspectives on cartilage as a specialized yet versatile tissue. This second volume is dedicated to basic pathologies of the two most common osteoarticular diseases affecting large segments of the Western population, osteoarthritis and chondrodysplasias. This book addresses Professors, ...

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  • Publisher : Harmony
  • Release Date : 2017-03-21
  • Total pages : 400
  • ISBN : 0128033223
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Summary : NEW YORK TIMES BESTSELLER • Reset your metabolism for lasting fat loss in one month and discover the carbs that are right for you. The surprising truth is that we are genetically wired to eat more and move less, the exact opposite of the advice we are often given. Now there ...

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  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-08-30
  • Total pages : 1744
  • ISBN : 0128033223
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Summary : Principles and Practice of Pediatric Infectious Disease provides the comprehensive and actionable coverage you need to understand, diagnose, and manage the ever-changing, high-risk clinical problems caused by pediatric infectious diseases. With new chapters, expanded and updated coverage, and increased worldwide perspectives, this authoritative medical reference offers the latest need-to-know information ...

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  • ISBN : 0128033223
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Summary : Download or read online Chapman s Comprehensive Orthopaedic Surgery written by Michael W Chapman,Michelle A James, published by JP Medical Ltd which was released on . Get Chapman s Comprehensive Orthopaedic Surgery Books now! Available in PDF, ePub and Kindle....

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  • Total pages : 760
  • ISBN : 0128033223
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Summary : Systemic disease involves several parts of the body or the complete system. Neurologic Aspects of Systemic Disease, a three-part volume in the Handbook of Clinical Neurology series, focuses on the specific neurologic aspects of systemic disease. Part 1 includes detailed coverage of cardiovascular disease, pulmonary diseases, renal diseases, and rheumatologic and ...

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  • Release Date : 2011-07-27
  • Total pages : 234
  • ISBN : 0128033223
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Summary : This book considers mainly etiology, pathogenesis, and pathophysiology of aortic aneurysms (AA) and aneurysm rupture and addresses anyone engaged in treatment and prevention of AA. Multiple factors are implicated in AA pathogenesis, and are outlined here in detail by a team of specialist researchers. Initial pathological events in AA involve ...

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  • ISBN : 0128033223
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Summary : Download or read online Retinal Changes in Neurological Diseases written by Yuyi You,Tim Magnus,Jianhai Du, published by Frontiers Media SA which was released on 2022-02-23. Get Retinal Changes in Neurological Diseases Books now! Available in PDF, ePub and Kindle....

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  • Publisher : Springer
  • Release Date : 2017-12-29
  • Total pages : 284
  • ISBN : 0128033223
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Summary : This book explains the underlying rationale for retinal and choroidal imaging in the context of systemic diseases. Various systemic diseases involve the eyes, and for some, the eyes could provide the first clue to their presence. Advances in posterior segment imaging have significantly improved our understanding of the pathophysiology and ...

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  • Publisher : SLACK Incorporated
  • Release Date : 2012
  • Total pages : 211
  • ISBN : 0128033223
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Summary : Uveitis specialists offer expert advice, preferences, and opinions on tough clinical questions commonly encountered by ophthalmologists, residents, and other health care professionals. The unique Q&A format provides quick access to current information related to uveitis with the simplicity of a conversation between two colleagues. Images, diagrams, and references are ...

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  • Author : Christine B. Boysen
  • Publisher : Nova Science Pub Incorporated
  • Release Date : 2013-01-01
  • Total pages : 65
  • ISBN : 0128033223
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Summary : Ankylosing spondylitis (AS) is a systemic inflammatory disease of unknown origin. In AS, spontaneous fusion of the sacroiliac joints and spine occurs due to chronic inflammation leading to initial back pain followed by generalised stiffness of the spine. In this book, the authors discuss the symptoms, treatment and potential complications ...

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  • Author : M. William Schwartz
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2003
  • Total pages : 1057
  • ISBN : 0128033223
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Summary : Now in its revised, updated Third Edition, this best-selling reference is designed for quick consultation on problems seen in infants, children, and adolescents. More than 450 problems are covered in the fast-access two-page outline format that makes The 5-Minute Consult Series titles so popular among busy clinicians. The book is organized ...

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  • Publisher : Elsevier Health Sciences
  • Release Date : 2015-09-16
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  • ISBN : 0128033223
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Summary : Get a firm grasp of disease and disease process as it relates to your job with Essentials of Human Diseases and Conditions, 6th Edition. Perfectly tailored to the needs to today’s medical assistants, this unique text uses simple language and an abundance of learning features as it walks readers ...