The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

Written By Joerg Bluemel
The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Publsiher : Academic Press
  • Release : 13 March 2015
  • ISBN : 012417146X
  • Pages : 716 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKThe Nonhuman Primate in Nonclinical Drug Development and Safety Assessment


Read or download book entitled The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment written by Joerg Bluemel which was release on 13 March 2015, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-13
  • Total pages : 716
  • ISBN : 012417146X
GET BOOK

Summary : The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, ...

Challenges in Nonhuman Primate Research in the 21st Century

Challenges in Nonhuman Primate Research in the 21st Century
  • Author : Gerhard F. Weinbauer,Friedhelm Vogel
  • Publisher : Waxmann Verlag
  • Release Date : 2013
  • Total pages : 180
  • ISBN : 012417146X
GET BOOK

Summary : In continuation of the Covance Primate Symposium Series, the 19th Covance Primate Symposium took place in Münster on 23rd & 24th of May 2012. Altogether, 70 participants representing 43 organisations, gathered for this symposium. The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate Research in the 21st Century?. The broad participation and the ...

Biomedical Product and Materials Evaluation

Biomedical Product and Materials Evaluation
  • Author : P.V. Mohanan
  • Publisher : Woodhead Publishing
  • Release Date : 2022-01-22
  • Total pages : 806
  • ISBN : 012417146X
GET BOOK

Summary : Biomedical Product and Materials Evaluation: Standards and Ethics provides a much-needed overview of the procedures, issues, standards and ethical issues in the early development of biomedical products. The book covers a range of key biomedical products, from 3D printed organs and blood derived products, to stem calls and decellularized tissue ...

Drug Discovery Toxicology

Drug Discovery Toxicology
  • Author : Yvonne Will,J. Eric McDuffie,Andrew J. Olaharski,Brandon D. Jeffy
  • Publisher : John Wiley & Sons
  • Release Date : 2016-03-22
  • Total pages : 584
  • ISBN : 012417146X
GET BOOK

Summary : As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers ...

The Laboratory Nonhuman Primate

The Laboratory Nonhuman Primate
  • Author : Jeffrey D. Fortman,Terry A. Hewett,Lisa C. Halliday
  • Publisher : CRC Press
  • Release Date : 2017-10-23
  • Total pages : 366
  • ISBN : 012417146X
GET BOOK

Summary : Extensively updated to include current literature, The Laboratory Nonhuman Primate, Second Edition, continues to serve as a quick reference source for technicians, caretakers, veterinarians, researchers, and students working with primates in biomedical research. It provides details on basic husbandry and covers biologic characteristics, regulatory compliance, common diseases, and anesthetic management. ...

Haschek and Rousseaux s Handbook of Toxicologic Pathology

Haschek and Rousseaux s Handbook of Toxicologic Pathology
  • Author : Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig,Brad Bolon
  • Publisher : Academic Press
  • Release Date : 2021-10-20
  • Total pages : 1152
  • ISBN : 012417146X
GET BOOK

Summary : Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three ...

Translational Medicine

Translational Medicine
  • Author : Joy A. Cavagnaro,Mary Ellen Cosenza
  • Publisher : CRC Press
  • Release Date : 2021-11-26
  • Total pages : 542
  • ISBN : 012417146X
GET BOOK

Summary : Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes ...

Drug Safety Evaluation

Drug Safety Evaluation
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2016-12-01
  • Total pages : 918
  • ISBN : 012417146X
GET BOOK

Summary : This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including ...

Pharmacoepidemiology and Pharmacovigilance

Pharmacoepidemiology and Pharmacovigilance
  • Author : Sabrina Nour,Gilles Plourde
  • Publisher : Academic Press
  • Release Date : 2018-10-17
  • Total pages : 144
  • ISBN : 012417146X
GET BOOK

Summary : Pharmacoepidemiology and Pharmacovigilance: Synergistic Tools to Better Investigate Drug Safety examines the role of pharmacoepidemiologic studies in drug development and its use as a prevention tool in pharmacovigilance activities. The book introduces the various epidemiologic tools and study designs commonly used for the surveillance of drug-related adverse effects and reviews ...

An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology
  • Author : Carey N. Pope,Jing Liu
  • Publisher : Academic Press
  • Release Date : 2020-02-18
  • Total pages : 644
  • ISBN : 012417146X
GET BOOK

Summary : An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, ...

Model Organisms for Microbial Pathogenesis Biofilm Formation and Antimicrobial Drug Discovery

Model Organisms for Microbial Pathogenesis  Biofilm Formation and Antimicrobial Drug Discovery
  • Author : Busi Siddhardha,Madhu Dyavaiah,Asad Syed
  • Publisher : Springer Nature
  • Release Date : 2020-03-28
  • Total pages : 684
  • ISBN : 012417146X
GET BOOK

Summary : This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm ...

Toxicologic Pathology for Non Pathologists

Toxicologic Pathology for Non Pathologists
  • Author : Thomas J. Steinbach,Daniel J. Patrick,Mary Ellen Cosenza
  • Publisher : Springer Nature
  • Release Date : 2019-10-31
  • Total pages : 919
  • ISBN : 012417146X
GET BOOK

Summary : This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help ...

Immunopathology in Toxicology and Drug Development

Immunopathology in Toxicology and Drug Development
  • Author : George A. Parker
  • Publisher : Springer
  • Release Date : 2017-03-27
  • Total pages : 826
  • ISBN : 012417146X
GET BOOK

Summary : This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an ...

Schalm s Veterinary Hematology

Schalm s Veterinary Hematology
  • Author : Marjory B. Brooks,Kendal E. Harr,Davis M. Seelig,K. Jane Wardrop,Douglas J. Weiss
  • Publisher : John Wiley & Sons
  • Release Date : 2022-02-24
  • Total pages : 1424
  • ISBN : 012417146X
GET BOOK

Summary : SCHALM’S VETERINARY HEMATOLOGY An updated guide to veterinary hematology with expanded coverage on a variety of topics The revised seventh edition of Schalm’s Veterinary Hematology is updated to provide a comprehensive review of all topics related to disorders of the blood in animals. Designed as a gold-standard reference, ...

Essentials of Laboratory Animal Science Principles and Practices

Essentials of Laboratory Animal Science  Principles and Practices
  • Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
  • Publisher : Springer Nature
  • Release Date : 2021-07-23
  • Total pages : 806
  • ISBN : 012417146X
GET BOOK

Summary : This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used ...