The Chemistry and Biology of Nitroxyl HNO

Written By Fabio Doctorovich
The Chemistry and Biology of Nitroxyl  HNO
  • Publsiher : Elsevier
  • Release : 01 September 2016
  • ISBN : 0128011645
  • Pages : 424 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled The Chemistry and Biology of Nitroxyl HNO written by Fabio Doctorovich which was release on 01 September 2016, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia

The Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl  HNO
  • Author : Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
  • Publisher : Elsevier
  • Release Date : 2016-09-01
  • Total pages : 424
  • ISBN : 0128011645
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Summary : The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed ...

Free Nitroxyl Radicals

Free Nitroxyl Radicals
  • Author : E. Rozantsev
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-14
  • Total pages : 249
  • ISBN : 0128011645
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Summary : In the short time since the first nitroxyl radical was obtained in 1959, a new branch of chemical science has arisen and taken shape-the chemistry of stable nitroxyl radicals. The present book was written by E. G. Rozantsev, one of the pioneers in this field and a prominent specialist on stable ...

Synthetic Explorations in the Pursuit of a Rapid Photoactivatable Nitroxyl Donor

Synthetic Explorations in the Pursuit of a Rapid  Photoactivatable  Nitroxyl Donor
  • Author : Mark Wesley Campbell
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 176
  • ISBN : 0128011645
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Summary : Nitroxyl (HNO) is a biologically relevant small molecule with considerable clinical promise for the treatment of heart failure. However, studies of the chemistry and biology of nitroxyl are hampered by its instability in aqueous solution. To aid in biological and chemical studies, nitroxyl donors (molecules that degrade to release HNO) ...

Oxidation and Antioxidants in Organic Chemistry and Biology

Oxidation and Antioxidants in Organic Chemistry and Biology
  • Author : Evgeny T. Denisov,Igor B. Afanas'ev
  • Publisher : CRC Press
  • Release Date : 2005-03-29
  • Total pages : 1024
  • ISBN : 0128011645
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Summary : Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information about mechanisms ...

Reactive Species Detection in Biology

Reactive Species Detection in Biology
  • Author : Frederick A. Villamena
  • Publisher : Elsevier
  • Release Date : 2016-10-23
  • Total pages : 340
  • ISBN : 0128011645
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Summary : Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy discusses the reactive oxygen species that have been implicated in the pathogenesis of various diseases, presenting theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, both in-vitro and in-vivo. Techniques covered include ...

Nitrification

Nitrification
  • Author : Bess B. Ward,Daniel J. Arp,Martin G. Klotz
  • Publisher : American Society for Microbiology Press
  • Release Date : 2011-03-25
  • Total pages : 454
  • ISBN : 0128011645
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Summary : A full review of the latest research findings on microbes involved in conventional aerobic nitrification, anaerobic ammonia oxidation, and related processes. • Examines the four principal groups of nitrifying microbes including conventional aerobic bacterial ammonia oxidizers, recently discovered aerobic archaeal ammonia oxidizers, anaerobic ammonia-oxidizing planctomycetes, and nitrite-oxidizing bacteria. • Provides current information ...

Bioactive Spin Labels

Bioactive Spin Labels
  • Author : Renat I. Zhdanov
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-29
  • Total pages : 636
  • ISBN : 0128011645
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Summary : Bioactive Spin Labels is a collection of contributions by leading experts on nitroxyl radicals and their application in biomedicine. These compounds are used as side specific contrast agents for in-vivo EPR techniques. Their potential as drugs is investigated. Bioactive Spin Labels is a must for researchers in bioorganic chemistry, pharmacology ...

Nitric Oxide

Nitric Oxide
  • Author : Lester Packer,Enrique Cadenas
  • Publisher : Gulf Professional Publishing
  • Release Date : 2005-09
  • Total pages : 664
  • ISBN : 0128011645
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Summary : Since the inception of the series, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all field of life sciences. This final volume in the five-part Nitric Oxide ...

Synthetic Chemistry of Stable Nitroxides

Synthetic Chemistry of Stable Nitroxides
  • Author : L. B. Volodarsky,V.A. Reznikov,V.I. Ovcharenko
  • Publisher : CRC Press
  • Release Date : 2017-11-22
  • Total pages : 236
  • ISBN : 0128011645
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Summary : This important book is devoted to covering the synthetic aspects of nitroxide chemistry. The problems of application and physicochemical properties of nitroxides are considered in the context of the choice of necessary radical structures, convenient precursors, and strategy of the synthesis. The book offers comparisons of the concrete classes of ...

Progress in Inorganic Chemistry

Progress in Inorganic Chemistry
  • Author : Kenneth D. Karlin
  • Publisher : John Wiley & Sons
  • Release Date : 2005-06-14
  • Total pages : 544
  • ISBN : 0128011645
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Summary : The cutting edge of scientific reporting . . . PROGRESS in Inorganic Chemistry Nowhere is creative scientific talent busier than in the world ofinorganic chemistry experimentation. Progress in InorganicChemistry continues in its tradition of being the most respectedavenue for exchanging innovative research. This series providesinorganic chemists and materials scientists with a forum forcritical, ...

Reactive Oxygen Species in Biological Systems An Interdisciplinary Approach

Reactive Oxygen Species in Biological Systems  An Interdisciplinary Approach
  • Author : Carol Colton,Daniel Gilbert
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-05-08
  • Total pages : 708
  • ISBN : 0128011645
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Summary : Reactive oxygen species (ROS) which include free radicals, peroxides, singlet oxygen, ozone, and nitrogen monoxide and dioxide free radicals, is an area of intense research. This volume covers (1) the destruction of cellular function by ROS resulting in pathological states; (2) the protection by ROS of an organism against invading organisms that ...

An Examination of the Physiologically Relevant Chemistry of Nitroxyl HNO

An Examination of the Physiologically Relevant Chemistry of Nitroxyl  HNO
  • Author : Natalie Mikki Cook
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 410
  • ISBN : 0128011645
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Summary : Download or read online An Examination of the Physiologically Relevant Chemistry of Nitroxyl HNO written by Natalie Mikki Cook, published by which was released on 2003. Get An Examination of the Physiologically Relevant Chemistry of Nitroxyl HNO Books now! Available in PDF, ePub and Kindle....

Porphyrins Advances in Research and Application 2011 Edition

Porphyrins  Advances in Research and Application  2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Total pages : 106
  • ISBN : 0128011645
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Summary : Porphyrins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Porphyrins. The editors have built Porphyrins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Porphyrins in this eBook to be ...

Nitric Oxide Part F

Nitric Oxide  Part F
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2011-09-02
  • Total pages : 512
  • ISBN : 0128011645
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Summary : The discovery that nitrogen monoxide or nitric oxide (NO)is a biologically produced free radical has revolutionized our thinking about physiological and pathological processes. This discovery has ignited enormous interest in the scientific community. When generated at low levels, NO is a signaling molecule, but at high concentration, NO is ...

Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
  • Author : D.L.H. Williams
  • Publisher : Elsevier
  • Release Date : 2004-12-16
  • Total pages : 280
  • ISBN : 0128011645
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Summary : Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and ...