TDP 43 and Neurodegeneration

Written By Vijay Kumar
TDP 43 and Neurodegeneration
  • Publsiher : Academic Press
  • Release : 23 October 2021
  • ISBN : 0128204400
  • Pages : 270 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled TDP 43 and Neurodegeneration written by Vijay Kumar which was release on 23 October 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. Reviews TDP-43 structure, folding, function, and pathology Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases Presents a systems and precision biology perspective of TDP-43 Discusses therapeutics of TDP-43 proteinopathies Translates bench research to application bedside

TDP 43 and Neurodegeneration

TDP 43 and Neurodegeneration
  • Author : Vijay Kumar,Manoj Kumar Jaiswal
  • Publisher : Academic Press
  • Release Date : 2021-10-23
  • Total pages : 270
  • ISBN : 0128204400
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Summary : Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s ...

Advanced Understanding of Neurodegenerative Diseases

Advanced Understanding of Neurodegenerative Diseases
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  • Publisher : BoD – Books on Demand
  • Release Date : 2011-12-16
  • Total pages : 456
  • ISBN : 0128204400
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Summary : Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand the etiology, ...

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Stem Cell Therapy for Organ Failure
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  • Publisher : Springer
  • Release Date : 2015-01-02
  • Total pages : 278
  • ISBN : 0128204400
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Summary : The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present ...

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Geriatric Neurology
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  • Publisher : Elsevier
  • Release Date : 2019-12-18
  • Total pages : 616
  • ISBN : 0128204400
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Summary : Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings ...

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Pathobiology of Human Disease
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2014-08-01
  • Total pages : 5000
  • ISBN : 0128204400
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Summary : Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different ...

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  • Publisher : Academic Press
  • Release Date : 2016-12-30
  • Total pages : 342
  • ISBN : 0128204400
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Summary : Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together ...