Novel Perspectives of Stem Cell Manufacturing and Therapies

• Author : Diana Kitala,Ana Colette Maurício
• Publisher : BoD – Books on Demand
• Release Date : 2021-04-14
• Total pages : 178
• ISBN : 1839625031

GET BOOK

Summary : In the 1950s, Nobel Prize winner Dr. E. Donnall Thomas was the first to successfully transplant hematopoietic stem cells. Since then, studies on stem cells have evolved and expanded worldwide. There are more than 650,000 scientific publications on stem cells and more than 8000 stem cell clinical trials. This book summarizes types ...

• Author : Joaquim M. S. Cabral,Claudia Lobato da Silva,Lucas G. Chase,Maria Margarida Diogo
• Publisher : Elsevier
• Release Date : 2016-07-24
• Total pages : 340
• ISBN : 1839625031

GET BOOK

Summary : Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the ...

• Author : Joaquim M. S. Cabral,Cláudia Lobato da Silva,Maria Margarida Diogo
• Publisher : MDPI
• Release Date : 2021-01-20
• Total pages : 170
• ISBN : 1839625031

GET BOOK

Summary : The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the ...

• Author : Mohamed Al-Rubeai,Mariam Naciri
• Publisher : Springer Science & Business Media
• Release Date : 2013-10-01
• Total pages : 189
• ISBN : 1839625031

GET BOOK

Summary : With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies ...

• Author : Firdos Alam Khan
• Publisher : Springer Nature
• Release Date : 2022-04-30
• Total pages : 272
• ISBN : 1839625031

GET BOOK

Summary : This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases. The book then reviews the ...

• Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
• Publisher : Springer
• Release Date : 2019-03-06
• Total pages : 173
• ISBN : 1839625031

GET BOOK

Summary : This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic ...

• Author : Franca Fagioli
• Publisher : Unknown
• Release Date : 2015
• Total pages : 212
• ISBN : 1839625031

GET BOOK

Summary : Mesenchymal stromal/stem cells (MSCs) are adult, self-renewable, multipotent cells that can be isolated in various tissues, most commonly bone marrow (BM) and adipose tissue. Because of their capacity for self-renewal and differentiation into tissues of mesodermal origin and due to their immunomodulatory ability, MSCs are used in many preclinical ...

• Author : Hematti Peiman,Sowmya Viswanathan
• Publisher : Academic Press
• Release Date : 2016-08-11
• Total pages : 362
• ISBN : 1839625031

GET BOOK

Summary : Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique ...

• Author : Adrian P. Gee
• Publisher : Springer Nature
• Release Date : 2021
• Total pages : 692
• ISBN : 1839625031

GET BOOK

Summary : This new edition presents a fully-updated and expanded look at current Good Manufacturing Practice (cGMP) for cell therapy products. It provides a complete discussion of facility design and operation including details specific to cord blood banking, cell processing, vector production and qualification of a new facility. Several chapters cover facility ...

• Author : Kursad Turksen
• Publisher : Humana Press
• Release Date : 2015-02-14
• Total pages : 220
• ISBN : 1839625031

GET BOOK

Summary : This volume collects a series of protocols describing the kinds of infrastructures, training, and standard operating procedures currently available to actualize the potential of stem cells for regenerative therapies. Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations pulls together key GMP techniques from laboratories around the world. Written ...

• Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Regenerative Medicine
• Publisher : National Academies Press
• Release Date : 2018-01-29
• Total pages : 124
• ISBN : 1839625031

GET BOOK

Summary : On June 26, 2017, the Forum on Regenerative Medicine hosted a public workshop in Washington, DC, titled Navigating the Manufacturing Process and Ensuring the Quality of Regenerative Medicine Therapies in order to examine and discuss the challenges, opportunities, and best practices associated with defining and measuring the quality of cell and tissue ...

• Author : Anthony Atala,Sean V. Murphy
• Publisher : Springer
• Release Date : 2014-08-28
• Total pages : 373
• ISBN : 1839625031

GET BOOK

Summary : This comprehensive volume is one of the first books to offer the reader detailed insight into sources of perinatal stem cells, their biology, and their potential for disease treatment. It examines the research and therapeutic applications of perinatal stem cells including the treatment of renal disease, hematopoietic regeneration, cardiac disease, ...

• Author : Raphael Gorodetsky,Richard Schäfer
• Publisher : Royal Society of Chemistry
• Release Date : 2011
• Total pages : 391
• ISBN : 1839625031

GET BOOK

Summary : This unique book by leading experts reviews the key therapeutic issues related to stem cell technology....

• Author : Babak Arjmand
• Publisher : Springer
• Release Date : 2016-12-01
• Total pages : 239
• ISBN : 1839625031

GET BOOK

Summary : This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each ...

• Author : Anthony Atala,Kyle J. Cetrulo,Rouzbeh R. Taghizadeh,Curtis L Cetrulo,Sean Murphy
• Publisher : Academic Press
• Release Date : 2018-06-14
• Total pages : 418
• ISBN : 1839625031

GET BOOK

Summary : Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers ...