Second Generation Cell and Gene Based Therapies

Written By Alain Vertes
Second Generation Cell and Gene Based Therapies
  • Publsiher : Academic Press
  • Release : 07 February 2020
  • ISBN : 0128120339
  • Pages : 846 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Second Generation Cell and Gene Based Therapies written by Alain Vertes which was release on 07 February 2020, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental technical advances remain to be achieved. Thus, this volume highlights the possible R&D paths, which will ultimately facilitate clinical delivery of cutting edge curative products. The next waves of innovation are reviewed in depth for hematopoietic stem cells, mesenchymal stem cells, tissue engineering, CAR-T cells, and cells of the immune system, as well as for enabling technologies such as gene and genome editing. Additionally, deep dives in product fundamentals, history of science, pathobiology of diseases, scientific and technological bases, and financing and technology adoption constraints are taken to unravel what will shape the cytotherapy industry to the horizon 2025 and beyond. The outcome is not simply a scientific book, but a global perspective on the nascent field combining science, business, and strategic fundamentals. Helps readers learn about the most current trends in cell-based therapy, their overall effectiveness from a clinical prospective, and how the industry is moving therapies forward for capitalization "Perspectives" section at the end of each chapter summarizes key learnings, hypotheses, and objectives highlighted and combines scientific and business insights Edited and authored by scientists representing both basic and clinical research and industry, presenting a complete story of the current state and future promise of cellular therapies

Second Generation Cell and Gene Based Therapies

Second Generation Cell and Gene Based Therapies
  • Author : Alain Vertes,Nathan J. Dowden,Devyn Smith,Nasib Qureshi
  • Publisher : Academic Press
  • Release Date : 2020-02-07
  • Total pages : 846
  • ISBN : 0128120339
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Summary : Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept ...

Cardiac Cell and Gene Transfer

Cardiac Cell and Gene Transfer
  • Author : Joseph M. Metzger
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-02-03
  • Total pages : 253
  • ISBN : 0128120339
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Summary : Heart disease is the leading cause of death in developed countries. Recent experimental advances featuring cellular, molecular, and genetic tools and technologies offer the potential for new therapeutic strategies directed toward remediation of inherited and acquired heart diseases. Whether these recent basic science advances will ultimately translate to clinical efficacy ...

New Targeting in The Reversal of Resistant Glioblastomas

New Targeting in The Reversal of Resistant Glioblastomas
  • Author : Ali Syed Arbab
  • Publisher : Academic Press
  • Release Date : 2021-03-05
  • Total pages : 202
  • ISBN : 0128120339
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Summary : New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect ...

Advances in Cell Based and Gene Based Therapies for Respiratory Diseases

Advances in Cell Based and Gene Based Therapies for Respiratory Diseases
  • Author : Miquéias Lopes-Pacheco,Fernanda Ferreira Cruz,Anna Dmitriyevna Krasnodembskaya,Johnatas Dutra Silva,Darcy Elizabeth Wagner
  • Publisher : Frontiers Media SA
  • Release Date : 2022-04-29
  • Total pages : 212
  • ISBN : 0128120339
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Summary : Prof. Wagner owns stock shares in Pfizer and Merck, patent pending on whole organ decellularisation and recelluarisation US20160067378A1. The other Topic Editors declare no competing interests with regards to the Research Topic theme....

Artificial Intelligence and Machine Learning in Healthcare

Artificial Intelligence and Machine Learning in Healthcare
  • Author : Ankur Saxena,Shivani Chandra
  • Publisher : Springer Nature
  • Release Date : 2021-05-06
  • Total pages : 228
  • ISBN : 0128120339
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Summary : This book reviews the application of artificial intelligence and machine learning in healthcare. It discusses integrating the principles of computer science, life science, and statistics incorporated into statistical models using existing data, discovering patterns in data to extract the information, and predicting the changes and diseases based on this data ...

Global Epidemiology of Cancer

Global Epidemiology of Cancer
  • Author : Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato
  • Publisher : John Wiley & Sons
  • Release Date : 2022-03-22
  • Total pages : 656
  • ISBN : 0128120339
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Summary : GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding ...

Epidemiology of Endocrine Tumors

Epidemiology of Endocrine Tumors
  • Author : Jahangir Moini,Craig Badolato,Raheleh Ahangari
  • Publisher : Elsevier
  • Release Date : 2021-02-17
  • Total pages : 568
  • ISBN : 0128120339
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Summary : Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. ...

Gene Based Therapies for Cancer

Gene Based Therapies for Cancer
  • Author : Jack A. Roth
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-07-28
  • Total pages : 278
  • ISBN : 0128120339
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Summary : Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety ...

Emerging Trends in Cell and Gene Therapy

Emerging Trends in Cell and Gene Therapy
  • Author : Michael K. Danquah,Ram I. Mahato
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-14
  • Total pages : 705
  • ISBN : 0128120339
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Summary : Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp ...

The Prospect of Industry 5 0 in Biomanufacturing

The Prospect of Industry 5 0 in Biomanufacturing
  • Author : Pau Loke Show,Kit Wayne Chew,Tau Chuan Ling
  • Publisher : CRC Press
  • Release Date : 2021-07-02
  • Total pages : 326
  • ISBN : 0128120339
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Summary : This is the first book to present the idea of Industry 5.0 in biomanufacturing and bioprocess engineering, both upstream and downstream. The Prospect of Industry 5.0 in Biomanufacturing details the latest technologies and how they can be used efficiently and explains process analysis from an engineering point of view. In addition, it ...

Braunwald s Heart Disease E Book

Braunwald s Heart Disease E Book
  • Author : Douglas L. Mann,Douglas P. Zipes,Peter Libby,Robert O. Bonow
  • Publisher : Elsevier Health Sciences
  • Release Date : 2014-07-30
  • Total pages : 2136
  • ISBN : 0128120339
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Summary : Ideal for cardiologists who need to keep abreast of rapidly changing scientific foundations, clinical research results, and evidence-based medicine, Braunwald’s Heart Disease is your indispensable source for definitive, state-of-the-art answers on every aspect of contemporary cardiology, helping you apply the most recent knowledge in personalized medicine, imaging techniques, pharmacology, ...

Advances In Pharmaceutical Cell Therapy Principles Of Cell based Biopharmaceuticals

Advances In Pharmaceutical Cell Therapy  Principles Of Cell based Biopharmaceuticals
  • Author : Huss Ralf,Guenther Christine,Hauser Andrea Josefine
  • Publisher : World Scientific
  • Release Date : 2015-09-23
  • Total pages : 564
  • ISBN : 0128120339
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Summary : This textbook is a comprehensive overview of the development of cell-based biopharmaceuticals. Beginning with the underlying biology of stem cell and cell-based products, it traces the long and complex journey from preclinical concept to initiation of a pivotal clinical trial and the potential business model behind it.The book also ...

Stem Cell and Gene Based Therapy

Stem Cell and Gene Based Therapy
  • Author : Alexander Battler,Jonathan Leor
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-06-26
  • Total pages : 460
  • ISBN : 0128120339
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Summary : Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major ...

Current Perspectives Challenges and Advances in Cell Based Therapies

Current Perspectives  Challenges and Advances in Cell Based Therapies
  • Author : Prashant Trikha,Monica Thakar,Conrad Russell Cruz
  • Publisher : Frontiers Media SA
  • Release Date : 2020-03-24
  • Total pages : 212
  • ISBN : 0128120339
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Summary : Download or read online Current Perspectives Challenges and Advances in Cell Based Therapies written by Prashant Trikha,Monica Thakar,Conrad Russell Cruz, published by Frontiers Media SA which was released on 2020-03-24. Get Current Perspectives Challenges and Advances in Cell Based Therapies Books now! Available in PDF, ePub and ...

Cell and Gene Therapies

Cell and Gene Therapies
  • Author : Miguel-Angel Perales,Syed A. Abutalib,Catherine Bollard
  • Publisher : Springer
  • Release Date : 2018-11-27
  • Total pages : 288
  • ISBN : 0128120339
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Summary : In this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ...