RNA Based Regulation in Human Health and Disease

Written By Anonim
RNA Based Regulation in Human Health and Disease
  • Publsiher : Academic Press
  • Release : 19 August 2020
  • ISBN : 0128171944
  • Pages : 444 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled RNA Based Regulation in Human Health and Disease written by Anonim which was release on 19 August 2020, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field

RNA Based Regulation in Human Health and Disease

RNA Based Regulation in Human Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-08-19
  • Total pages : 444
  • ISBN : 0128171944
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Summary : RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and ...

Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-09-12
  • Total pages : 444
  • ISBN : 0128171944
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Summary : Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly ...

Epigenetics of the Immune System

Epigenetics of the Immune System
  • Author : Dieter Kabelitz,Jaydeep Bhat
  • Publisher : Academic Press
  • Release Date : 2020-06-04
  • Total pages : 384
  • ISBN : 0128171944
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Summary : Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, ...

Epigenetics Methods

Epigenetics Methods
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2020-07-08
  • Total pages : 736
  • ISBN : 0128171944
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Summary : In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools ...

microRNA Regulation in Health and Disease

microRNA Regulation in Health and Disease
  • Author : Clifford J. Steer,Subbaya Subramanian
  • Publisher : MDPI
  • Release Date : 2020-02-21
  • Total pages : 154
  • ISBN : 0128171944
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Summary : MicroRNAs (miRNAs) are small regulatory RNAs that play a crucial role in posttranscriptional gene regulation. Over two thousand miRNAs have been identified in humans, and many of them are conserved in other species. miRNAs are implicated in fundamental cellular functions, including development and disease. In the last decade, there has ...

microRNA Regulation in Health and Disease

microRNA Regulation in Health and Disease
  • Author : Clifford Steer,Subree Subramanian
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 154
  • ISBN : 0128171944
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Summary : MicroRNAs (miRNAs) are small regulatory RNAs that play a crucial role in posttranscriptional gene regulation. Over two thousand miRNAs have been identified in humans, and many of them are conserved in other species. miRNAs are implicated in fundamental cellular functions, including development and disease. In the last decade, there has ...

Medical Epigenetics

Medical Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2016-06-21
  • Total pages : 924
  • ISBN : 0128171944
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Summary : Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of ...

NLRP3 Inflammasome Regulatory Mechanisms Role in Health and Disease and Therapeutic Potential

NLRP3 Inflammasome  Regulatory Mechanisms  Role in Health and Disease and Therapeutic Potential
  • Author : Kuo-Feng Hua,Oleg Chernikov,Ann Chen,Jong-Seok Moon
  • Publisher : Frontiers Media SA
  • Release Date : 2021-11-08
  • Total pages : 212
  • ISBN : 0128171944
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Summary : Download or read online NLRP3 Inflammasome Regulatory Mechanisms Role in Health and Disease and Therapeutic Potential written by Kuo-Feng Hua,Oleg Chernikov,Ann Chen,Jong-Seok Moon, published by Frontiers Media SA which was released on 2021-11-08. Get NLRP3 Inflammasome Regulatory Mechanisms Role in Health and Disease and Therapeutic Potential ...

Evidence Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease

Evidence Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease
  • Author : Asim K. Duttaroy
  • Publisher : Academic Press
  • Release Date : 2021-07-08
  • Total pages : 472
  • ISBN : 0128171944
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Summary : Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease explores a wide range of studies from clinical investigations to mechanistic research, covering the actions of bioactives on specific tissues and cells in intestinal, neurological, immunological and cardiovascular health and disease, including cancers. The book also focuses ...

Regulatory microRNA

Regulatory microRNA
  • Author : Y-h. Taguchi,Hsiuying Wang
  • Publisher : MDPI
  • Release Date : 2019-04-16
  • Total pages : 348
  • ISBN : 0128171944
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Summary : This book includes updated information about microRNA regulation, for example, in the fields of circular RNAs, multiomics analysis, biomarkers and oncogenes. The variety of topics included in this book reaffirms the extent to which microRNA regulation affects biological processes. Although microRNAs are not translated to proteins, their importance for biological ...

Environmental Epigenomics in Health and Disease

Environmental Epigenomics in Health and Disease
  • Author : Randy L. Jirtle,Frederick L. Tyson
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-05-13
  • Total pages : 339
  • ISBN : 0128171944
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Summary : There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without ...

Molecular Biology of Long Non coding RNAs

Molecular Biology of Long Non coding RNAs
  • Author : Ahmad M. Khalil
  • Publisher : Springer
  • Release Date : 2019-06-06
  • Total pages : 187
  • ISBN : 0128171944
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Summary : This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely ...

Free Radicals in Human Health and Disease

Free Radicals in Human Health and Disease
  • Author : Vibha Rani,Umesh Chand Singh Yadav
  • Publisher : Springer
  • Release Date : 2014-11-14
  • Total pages : 430
  • ISBN : 0128171944
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Summary : The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and ...

Redox Signaling and Regulation in Biology and Medicine

Redox Signaling and Regulation in Biology and Medicine
  • Author : Claus Jacob,Paul G. Winyard
  • Publisher : John Wiley & Sons
  • Release Date : 2009-05-06
  • Total pages : 514
  • ISBN : 0128171944
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Summary : This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect ...

Glutathione and Sulfur Amino Acids in Human Health and Disease

Glutathione and Sulfur Amino Acids in Human Health and Disease
  • Author : Roberta Masella,Giuseppe Mazza
  • Publisher : John Wiley & Sons
  • Release Date : 2009-08-06
  • Total pages : 528
  • ISBN : 0128171944
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Summary : The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance ...