Resident Stem Cells and Regenerative Therapy

Written By Regina Coeli dos Santos Goldenberg
Resident Stem Cells and Regenerative Therapy
  • Publsiher : Academic Press
  • Release : 25 June 2022
  • ISBN : 0124160123
  • Pages : 270 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Resident Stem Cells and Regenerative Therapy written by Regina Coeli dos Santos Goldenberg which was release on 25 June 2022, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures. This book will present the main findings to date and the important factors to be considered when considering resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin, and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. Highlights basic research in tissue specific stem cells, experiments with animal models and clinical trials that are transforming the field of regeneration Provides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future research Reports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications

Resident Stem Cells and Regenerative Therapy

Resident Stem Cells and Regenerative Therapy
  • Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
  • Publisher : Academic Press
  • Release Date : 2012
  • Total pages : 270
  • ISBN : 0124160123
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Summary : In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery ...

Fetal Stem Cells in Regenerative Medicine

Fetal Stem Cells in Regenerative Medicine
  • Author : Dario O. Fauza,Mahmud Bani
  • Publisher : Springer
  • Release Date : 2016-05-02
  • Total pages : 453
  • ISBN : 0124160123
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Summary : This book explores the regenerative properties of fetal stem cells, from feto-maternal cell traffic through perinatal stem cells, with a discussion of key topics including stem cell banking, drug screening, in utero stem cell transplantation and ethical considerations. The expertly authored chapters also delve into embryonic, amniotic membrane, and umbilical ...

Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine

Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine
  • Author : Yan Nie
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0124160123
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Summary : Stem cell therapy is a promising option for regenerative of injured or diseased tissues. However, the extremely low survival and engraftment of transplanted cells and the obviously inadequate recruitment and activation of the endogenous resident stem cells are the major challenges for stem cell therapy. Fortunately, recent progresses show that ...

Adult Stem Cells

Adult Stem Cells
  • Author : Donald G. Phinney
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-02-11
  • Total pages : 279
  • ISBN : 0124160123
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Summary : This is comprehensive overview of a vital area of scientific enquiry, which covers a broad spectrum of issues. With contributions from some of the key researchers in the field, Adult Stem Cells: Biology and Methods of Analysis offers readers a historical perspective as well as unique insights into cutting-edge thoughts. ...

Resident Stem Cells and Regenerative Therapy

Resident Stem Cells and Regenerative Therapy
  • Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
  • Publisher : Academic Press
  • Release Date : 2012-12-31
  • Total pages : 304
  • ISBN : 0124160123
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Summary : In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery ...

Stem Cell Assays

Stem Cell Assays
  • Author : Nagarajan Kannan,Philip Beer
  • Publisher : Humana
  • Release Date : 2022-05-05
  • Total pages : 569
  • ISBN : 0124160123
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Summary : This volume explores the fields of stem cell biology, regenerative medicine, and cancer biology. The chapters in this book cover topics such as embryonic stem cells (ES) and induced pluripotent cells (iPS); ES/iPSC derived tissue stem cells; tissue resident stem cells; assays for primitive malignant cells; and CRISPR/Cas9 ...

Stem Cell Biology and Regenerative Medicine in Ophthalmology

Stem Cell Biology and Regenerative Medicine in Ophthalmology
  • Author : Stephen Tsang
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-09
  • Total pages : 188
  • ISBN : 0124160123
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Summary : Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, ...

Gene Therapy and Cell Fusion Enhances Stem Cell Mediated Cardiac Repair

Gene Therapy and Cell Fusion Enhances Stem Cell Mediated Cardiac Repair
  • Author : Pearl Jennine Quijada
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 130
  • ISBN : 0124160123
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Summary : Cardiovascular disease is the leading cause of mortality in the United States. Myocardial infarction (MI) induces massive cellular death and leads to a decline in cardiac function. Cardiomyocytes have limited proliferative capacity sparking interests in molecular and cellular strategies to promote stem cell conversion into new cardiomyocytes. Cardiac progenitor cells (...

Frontiers in Stem Cell and Regenerative Medicine Research

Frontiers in Stem Cell and Regenerative Medicine Research
  • Author : Atta-ur Rahman,Shazia Anjum
  • Publisher : Bentham Science Publishers
  • Release Date : 2017-05-11
  • Total pages : 253
  • ISBN : 0124160123
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Summary : Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing ...

Role of Stem Cells and Extracellular Matrix in the Regeneration of Skeletal Muscle

Role of Stem Cells and Extracellular Matrix in the Regeneration of Skeletal Muscle
  • Author : Andrew Dunn
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0124160123
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Summary : Adult skeletal muscle has a remarkable capacity to initiate a rapid and extensive repair process after damage due to injury or degenerative disease. Although satellite cells are the primary skeletal muscle stem cells, there are many reports of non-satellite cell populations with myogenic capacity resident within skeletal muscle. The activity ...

Roles and Regulation of Satellite Cells in Skeletal Muscle Regeneration

Roles and Regulation of Satellite Cells in Skeletal Muscle Regeneration
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2021
  • Total pages : 23
  • ISBN : 0124160123
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Summary : Skeletal muscle has an innate ability to self-regenerate in response to certain stimuli. In the case of trauma, muscle resident stem cells are required to meet the regenerative needs of the tissue. These resident stem cells, called satellite cells (SCs), are crucial in the regenerative process following injury; understanding the ...

Human Pluripotent Stem Cell derived Mesothelium Functions in Regenerative Medicine as a Multipotent Vascular Progenitor

Human Pluripotent Stem Cell derived Mesothelium Functions in Regenerative Medicine as a Multipotent Vascular Progenitor
  • Author : Thomas Anthony Colunga
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0124160123
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Summary : The human body contains two major coelomic cavities, thoracic and abdominal, that are lined with an epithelial cell called mesothelium. Mesothelium also forms the outer layer of internal organs within these cavities and an additional protective pouch surrounding the heart called the pericardium. Mesothelium contributes to the development of the ...

Multimodal Nanoparticles for Image guided Delivery of Mesenchymal Stem Cells in the Treatment of Myocardial Infarction

Multimodal Nanoparticles for Image guided Delivery of Mesenchymal Stem Cells in the Treatment of Myocardial Infarction
  • Author : Sean Sweeney
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 135
  • ISBN : 0124160123
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Summary : One of the leading causes of death and hospital stays in the United States, myocardial infarction (MI) occurs when coronary blockages lead to downstream ischemia in the myocardium. Following the MI, the heart activates a number of pathways to repair or remodel the infarcted zone. Endothelial cells respond to ischemia ...

The Vascular Niche in Tissue Repair A Therapeutic Target for Regeneration

The Vascular Niche in Tissue Repair  A Therapeutic Target for Regeneration
  • Author : Francisco J. Rivera,Ludwig Aigner
  • Publisher : Frontiers Media SA
  • Release Date : 2018-03-13
  • Total pages : 212
  • ISBN : 0124160123
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Summary : Tissues and organs have, although sometimes limited, the capacity for endogenous repair, which is aimed to re-establish integrity and homeostasis. Tissue repair involves pro- and anti-inflammatory processes, new tissue formation and remodelling. Depending on the local microenvironment, tissue repair results either in scar tissue formation or in regeneration. The latter ...

Stem Cell and Regenerative Medicine

Stem Cell and Regenerative Medicine
  • Author : Herman S. Cheung
  • Publisher : Bentham Science Publishers
  • Release Date : 2010-12-10
  • Total pages : 173
  • ISBN : 0124160123
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Summary : "The potential use of stem cells in transplantation for the purpose of tissue regeneration is an exciting area of research currently undergoing rapid development. Implantation of human embryonic or autologous, ex vivo-expanded adult stem cells, particularl"...