Proteomic and Metabolomic Approaches to Biomarker Discovery

Written By Haleem J. Issaq
Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Publsiher : Academic Press
  • Release : 24 October 2019
  • ISBN : 0128197889
  • Pages : 504 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Proteomic and Metabolomic Approaches to Biomarker Discovery written by Haleem J. Issaq which was release on 24 October 2019, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research. Addresses the full range of proteomic and metabolomic methods and technologies used for biomarker discovery and validation Covers all steps involved in biomarker discovery, from study design to study execution Serves as a vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals and graduate students

Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Author : Haleem J. Issaq,Timothy D. Veenstra
  • Publisher : Academic Press
  • Release Date : 2019-10-24
  • Total pages : 504
  • ISBN : 0128197889
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Summary : Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data ...

The Detection of Biomarkers

The Detection of Biomarkers
  • Author : Sibel A. Ozkan,Nurgul K. Bakirhan,Fariba Mollaraosouli
  • Publisher : Academic Press
  • Release Date : 2021-12-05
  • Total pages : 614
  • ISBN : 0128197889
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Summary : Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for ...

Emerging Sample Treatments in Proteomics

Emerging Sample Treatments in Proteomics
  • Author : José-Luis Capelo-Martínez
  • Publisher : Springer
  • Release Date : 2019-06-24
  • Total pages : 222
  • ISBN : 0128197889
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Summary : Proteomics is a well-established area of Science; yet with a strong area in constant evolution, namely sample treatment. There few books that currently cover the field of emerging sample treatments in proteomics, this new volume will be the first to cover all emerging and existing studies. This unique book presents ...

Biomarker Discovery in the Developing World Dissecting the Pipeline for Meeting the Challenges

Biomarker Discovery in the Developing World  Dissecting the Pipeline for Meeting the Challenges
  • Author : Sanjeeva Srivastava
  • Publisher : Springer
  • Release Date : 2016-09-30
  • Total pages : 118
  • ISBN : 0128197889
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Summary : This book is oriented towards post-graduates and researchers with interest in proteomics and its applications in clinical biomarker discovery pipeline. Biomarker discovery has long been the research focus of many life scientists globally. However, the pipeline starting from discovery to validation to regulation as a diagnostic or therapeutic molecule follows ...

Proteomic Applications in Cancer Detection and Discovery

Proteomic Applications in Cancer Detection and Discovery
  • Author : Timothy D. Veenstra
  • Publisher : John Wiley & Sons
  • Release Date : 2013-05-30
  • Total pages : 320
  • ISBN : 0128197889
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Summary : Helps researchers in proteomics and oncology work together tounderstand, prevent, and cure cancer Proteomic data is increasingly important to understanding theorigin and progression of cancer; however, most oncologicresearchers who depend on proteomics for their studies do notcollect the data themselves. As a result, there is a knowledge gapbetween scientists, who ...

AGO Driven Non Coding RNAs

AGO Driven Non Coding RNAs
  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Release Date : 2019-01-20
  • Total pages : 387
  • ISBN : 0128197889
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Summary : The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily ...

Multi omic Data Integration

Multi omic Data Integration
  • Author : Paolo Tieri,Christine Nardini,Jennifer Elizabeth Dent
  • Publisher : Frontiers Media SA
  • Release Date : 2015-09-17
  • Total pages : 212
  • ISBN : 0128197889
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Summary : Stable, predictive biomarkers and interpretable disease signatures are seen as a significant step towards personalized medicine. In this perspective, integration of multi-omic data coming from genomics, transcriptomics, glycomics, proteomics, metabolomics is a powerful strategy to reconstruct and analyse complex multi-dimensional interactions, enabling deeper mechanistic and medical insight. At the same ...

Proceedings of Agriculture Biotechnology Sustainability Conference Oral papers

Proceedings of Agriculture  Biotechnology   Sustainability Conference  Oral papers
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128197889
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Summary : Download or read online Proceedings of Agriculture Biotechnology Sustainability Conference Oral papers written by , published by which was released on 2009. Get Proceedings of Agriculture Biotechnology Sustainability Conference Oral papers Books now! Available in PDF, ePub and Kindle....

Genetic Programming for Biomarker Detection in Classification of Mass Spectrometry Data

Genetic Programming for Biomarker Detection in Classification of Mass Spectrometry Data
  • Author : Soha Ahmed
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 246
  • ISBN : 0128197889
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Summary : Mass spectrometry (MS) is currently the most commonly used technology in biochemical research for proteomic analysis. The primary goal of proteomic profiling using mass spectrometry is the classification of samples from different experimental states. To classify the MS samples, the identification of protein or peptides (biomarker detection) that are expressed ...

The Handbook of Biomarkers

The Handbook of Biomarkers
  • Author : Kewal K. Jain
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-02-06
  • Total pages : 492
  • ISBN : 0128197889
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Summary : Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of ...

Proteomics in Nephrology

Proteomics in Nephrology
  • Author : Visith Thongboonkerd
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2008
  • Total pages : 203
  • ISBN : 0128197889
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Summary : Since the publication of the first volume on proteomics in nephrology, methodologies and protocols for renal and urinary proteome analyses have been continuously improved, resulting in considerable progress towards clinical application. Proteomics not only contributes to a better understanding of the renal physiology and pathogenic mechanisms of kidney diseases, but ...

Radiation Proteomics

Radiation Proteomics
  • Author : Dariusz Leszczynski
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-02-03
  • Total pages : 130
  • ISBN : 0128197889
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Summary : Methods of proteomics have been shown to be powerful tools in search of target proteins – proteins that respond in cells to an internal or an external stimulus. Proteomics is widely used in biomedical research. However, in radiation biology research, following exposures of living matter to low doses of either ionizing ...

Clinical Proteomics

Clinical Proteomics
  • Author : Jennifer E. Van Eyk,Michael J. Dunn
  • Publisher : John Wiley & Sons
  • Release Date : 2008-09-08
  • Total pages : 694
  • ISBN : 0128197889
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Summary : Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of ...

Textbook of Veterinary Internal Medicine

Textbook of Veterinary Internal Medicine
  • Author : Stephen J. Ettinger,Edward C. Feldman
  • Publisher : Unknown
  • Release Date : 2010
  • Total pages : 2218
  • ISBN : 0128197889
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Summary : "Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, ...

Predictive Approaches in Drug Discovery and Development

Predictive Approaches in Drug Discovery and Development
  • Author : J. Andrew Williams,Richard Lalonde,Jeffrey R. Koup,David D. Christ
  • Publisher : John Wiley & Sons
  • Release Date : 2012-04-10
  • Total pages : 408
  • ISBN : 0128197889
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Summary : Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with ...