Polymers and Nanomaterials for Gene Therapy

Written By Ravin Narain
Polymers and Nanomaterials for Gene Therapy
  • Publsiher : Woodhead Publishing
  • Release : 09 January 2016
  • ISBN : 0081005210
  • Pages : 302 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Polymers and Nanomaterials for Gene Therapy written by Ravin Narain which was release on 09 January 2016, this book published by Woodhead Publishing. Available in PDF, EPUB and Kindle Format. Book excerpt: Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications

Polymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy
  • Author : Ravin Narain
  • Publisher : Woodhead Publishing
  • Release Date : 2016-01-09
  • Total pages : 302
  • ISBN : 0081005210
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Summary : Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides ...

Polymer Science and Nanotechnology

Polymer Science and Nanotechnology
  • Author : Ravin Narain
  • Publisher : Elsevier
  • Release Date : 2020-06-16
  • Total pages : 488
  • ISBN : 0081005210
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Summary : Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest ...

Advances in Nanomaterials in Biomedicine

Advances in Nanomaterials in Biomedicine
  • Author : Elena I. Ryabchikova
  • Publisher : MDPI
  • Release Date : 2021-09-01
  • Total pages : 472
  • ISBN : 0081005210
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Summary : "Advances in Nanomaterials in Biomedicine" provided a platform for more than 110 researchers from different countries to present their latest investigations in various fields of nanotechnology, new methods and nanomaterials intended for medical applications. Modern achievements in the field of nanoparticle-based diagnostics, drug delivery and the use of various nanomaterials in ...

Multifunctional Polymeric Materials for Drug and Gene Delivery

Multifunctional Polymeric Materials for Drug and Gene Delivery
  • Author : Yakai Feng,Abraham Jacob Domb,Bin He,Wenzhong Li
  • Publisher : Frontiers Media SA
  • Release Date : 2022-05-30
  • Total pages : 212
  • ISBN : 0081005210
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Summary : Download or read online Multifunctional Polymeric Materials for Drug and Gene Delivery written by Yakai Feng,Abraham Jacob Domb,Bin He,Wenzhong Li, published by Frontiers Media SA which was released on 2022-05-30. Get Multifunctional Polymeric Materials for Drug and Gene Delivery Books now! Available in PDF, ePub and ...

Gene and Cell Therapy Biology and Applications

Gene and Cell Therapy  Biology and Applications
  • Author : Giridhara R. Jayandharan
  • Publisher : Springer
  • Release Date : 2018-09-12
  • Total pages : 305
  • ISBN : 0081005210
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Summary : Recent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) ...

Polymeric Gene Delivery Systems

Polymeric Gene Delivery Systems
  • Author : Yiyun Cheng
  • Publisher : Springer
  • Release Date : 2018-09-04
  • Total pages : 358
  • ISBN : 0081005210
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Summary : ‚ÄčThe series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume ...

New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications

New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications
  • Author : Marc J.M. Abadie,Mariana Pinteala,Alexandru Rotaru
  • Publisher : Springer Nature
  • Release Date : 2021-05-26
  • Total pages : 371
  • ISBN : 0081005210
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Summary : This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment ...

Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2018-10-26
  • Total pages : 558
  • ISBN : 0081005210
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Summary : Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy ...

Advances in Nanomaterials for Drug Delivery

Advances in Nanomaterials for Drug Delivery
  • Author : Mahdi Karimi,Maryam Rad Mansouri,Navid Rabiee,Michael R Hamblin
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2018-12-05
  • Total pages : 78
  • ISBN : 0081005210
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Summary : Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery ...

Bio Inspired Nanomaterials and Applications

Bio Inspired Nanomaterials and Applications
  • Author : Donglu Shi
  • Publisher : World Scientific
  • Release Date : 2014-11-18
  • Total pages : 256
  • ISBN : 0081005210
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Summary : This book intends to provide an up-to-date information in the field of nanobiomedicine. The focus of the book is on the basic concepts and recent developments in the field of nanotechnology. This book covers a broad spectrum of nanomaterials processing, structural characteristics, and related properties and will include bio-probes, medical ...

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications
  • Author : Abdel Salam Hamdy Makhlouf,Nedal Y. Abu-Thabit
  • Publisher : Woodhead Publishing
  • Release Date : 2018-06-14
  • Total pages : 692
  • ISBN : 0081005210
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Summary : Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume One: Types and Triggers discusses, in detail, the recent trends in designing biodegradable and biocompatible single-responsive polymers and nanoparticles for safe drug delivery. Focusing on the most advanced materials and technologies, evaluation methods, and advanced synthesis techniques stimuli-responsive polymers, the book ...

Nanoparticulate Drug Delivery

Nanoparticulate Drug Delivery
  • Author : Vandana Patravale,Prajakta Dandekar,Ratnesh Jain
  • Publisher : Elsevier
  • Release Date : 2012-10-31
  • Total pages : 244
  • ISBN : 0081005210
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Summary : Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery ...

Biomedical Applications of Polymeric Materials and Composites

Biomedical Applications of Polymeric Materials and Composites
  • Author : Raju Francis,D. Sakthi Kumar
  • Publisher : John Wiley & Sons
  • Release Date : 2016-09-16
  • Total pages : 416
  • ISBN : 0081005210
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Summary : With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications. Following an introduction listing various functional polymers, including conductive, biocompatible and conjugated polymers, the book goes on to discuss different synthetic polymers that can be used, ...

New Nanomaterials and Techniques for Tumor targeted Systems

New Nanomaterials and Techniques for Tumor targeted Systems
  • Author : Rongqin Huang,Yi Wang
  • Publisher : Springer Nature
  • Release Date : 2020-09-28
  • Total pages : 463
  • ISBN : 0081005210
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Summary : This book summarizes the latest advances in nanomaterials and techniques in the field of tumor-targeted diagnosis and therapy. It provides valuable information for beginners and senior researchers, and stimulates new research directions by offering novel and provocative insights into the properties and technical principles of nanomaterials. The book systemically discusses ...

Nonviral Vectors for Gene Therapy

Nonviral Vectors for Gene Therapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2014-11-18
  • Total pages : 428
  • ISBN : 0081005210
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Summary : The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Includes methods for testing with ethical, legal, and ...