Phenotypic Switching

Written By Herbert Levine
Phenotypic Switching
  • Publsiher : Academic Press
  • Release : 10 June 2020
  • ISBN : 012817997X
  • Pages : 762 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Phenotypic Switching written by Herbert Levine which was release on 10 June 2020, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications in cancer therapy, regenerative medicine and stem cell therapy, among other treatments. Chapters discuss fundamental mechanisms of phenotypic switching, including transition states, cell fate decisions, epigenetic factors, stochasticity, protein-based inheritance, specific areas of human development and disease relevance, phenotypic plasticity in melanoma, prostate cancer, breast cancer, non-genetic heterogeneity in cancer, hepatitis C, and more. This book is essential for active researchers, basic and translational scientists, clinicians, postgraduates and students in genetics, human genomics, pathology, bioinformatics, developmental biology, evolutionary biology and adaptive opportunities in yeast. Thoroughly addresses the conceptual, experimental and translational aspects that underlie phenotypic plasticity Emphasizes quantitative approaches, nonlinear dynamics, mechanistic insights and key methodologies to advance phenotypic plasticity studies Features a diverse range of chapter contributions from international leaders in the field

Phenotypic Switching

Phenotypic Switching
  • Author : Herbert Levine,Mohit Kumar Jolly,Prakash Kulkarni,Vidyanand Nanjundiah
  • Publisher : Academic Press
  • Release Date : 2020-06-10
  • Total pages : 762
  • ISBN : 012817997X
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Summary : Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications ...

A Mechanistic and Functional Study of White opaque Phenotypic Switching in Candida Albicans

A Mechanistic and Functional Study of White opaque Phenotypic Switching in Candida Albicans
  • Author : Mathew Gregory Miller
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 340
  • ISBN : 012817997X
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Summary : Candida albicans is a major fungal pathogen of humans. It is a harmless commensal in healthy individuals, but it can cause serious infections in immune-compromised hosts. C. albicans undergoes a meta-stable and reversible switch between two distinct cell types known as white and opaque. The role of white-opaque switching in ...

Molecular Biology of Fungal Development

Molecular Biology of Fungal Development
  • Author : Heinz D. Osiewacz
  • Publisher : CRC Press
  • Release Date : 2002-05-07
  • Total pages : 608
  • ISBN : 012817997X
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Summary : This text gives an overview of the fundamental aspects of molecular fungal development in one comprehensive volume, highlighting different elements in the maturational and reproductive cycles of selected fungal taxa....

Cellular and Phenotypic Plasticity in Cancer

Cellular and Phenotypic Plasticity in Cancer
  • Author : Petranel Theresa Ferrao,Andreas Behren,Robin Anderson, Erik Thompson
  • Publisher : Unknown
  • Release Date : 2015-09-17
  • Total pages : 212
  • ISBN : 012817997X
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Summary : The process of Epithelial-Mesenchymal-Transition (EMT) is known to result in a phenotype change in cells from a proliferative state to a more invasive state. EMT has been reported to drive the metastatic spread of various cancers and has also been associated with drug resistance to cytotoxics and targeted therapeutics. Recently ...

Growing Fungus

Growing Fungus
  • Author : N.A. Gow,Geoffrey M. Gadd
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-08-28
  • Total pages : 473
  • ISBN : 012817997X
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Summary : This book is about the growth and differentiation processes underlying the growth and differentia of filamentous fungi. The impetus for this work tion of fungi and that it provides the reader with stems from our perception that the coverage of adequate source references for further information. this highly diverse and ...

Handbook of Epigenetics

Handbook of Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2017-07-10
  • Total pages : 682
  • ISBN : 012817997X
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Summary : Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable ...

Stochastic Processes in Cell Biology

Stochastic Processes in Cell Biology
  • Author : Paul C. Bressloff
  • Publisher : Springer Nature
  • Release Date : 2021
  • Total pages : 724
  • ISBN : 012817997X
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Summary : This book develops the theory of continuous and discrete stochastic processes within the context of cell biology. In the second edition the material has been significantly expanded, particularly within the context of nonequilibrium and self-organizing systems. Given the amount of additional material, the book has been divided into two volumes, ...

New Insights in Medical Mycology

New Insights in Medical Mycology
  • Author : Kevin Kavanagh
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-09-18
  • Total pages : 289
  • ISBN : 012817997X
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Summary : The aim of this book is to give an in-depth assessment of our current understanding of the Biology of the main fungal pathogens and how they interact with the host’s immune response. Each chapter focuses on a specific fungal pathogen or group of pathogens, and examines their biology and ...

Dancing Protein Clouds Intrinsically Disordered Proteins in the Norm and Pathology

Dancing Protein Clouds  Intrinsically Disordered Proteins in the Norm and Pathology
  • Author : Vladimir Uversky
  • Publisher : Academic Press
  • Release Date : 2019-09-15
  • Total pages : 424
  • ISBN : 012817997X
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Summary : "Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their ...

Emerging Trends in Cell and Gene Therapy

Emerging Trends in Cell and Gene Therapy
  • Author : Michael K. Danquah,Ram I. Mahato
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-14
  • Total pages : 705
  • ISBN : 012817997X
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Summary : Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp ...

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases
  • Author : Jun Sun,Pradeep K. Dudeja
  • Publisher : Springer
  • Release Date : 2018-01-26
  • Total pages : 381
  • ISBN : 012817997X
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Summary : Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis ...

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease
  • Author : Robert Fitridge
  • Publisher : Springer Nature
  • Release Date : 2020-07-30
  • Total pages : 733
  • ISBN : 012817997X
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Summary : This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a ...

Pseudomonas

Pseudomonas
  • Author : Juan-Luis Ramos
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-06-28
  • Total pages : 835
  • ISBN : 012817997X
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Summary : Pseudomonas comprises three volumes covering the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human ...

Endodontic Microbiology

Endodontic Microbiology
  • Author : Ashraf F. Fouad
  • Publisher : John Wiley & Sons
  • Release Date : 2017-01-24
  • Total pages : 472
  • ISBN : 012817997X
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Summary : Endodontic Microbiology, Second Edition presents a comprehensive reference to the microbiology, pathogenesis, management, and healing of endodontic pathosis, emphasizing the importance of biological sciences in understanding and managing endodontic disease and its interaction with systemic health. Provides a major revision to the first book to focus on the problems related ...

Advances in Extracellular Space Research and Application 2011 Edition

Advances in Extracellular Space Research and Application  2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Total pages : 260
  • ISBN : 012817997X
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Summary : Advances in Extracellular Space Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Extracellular Space. The editors have built Advances in Extracellular Space Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Extracellular Space in ...