Phase I Cancer Clinical Trials

Written By Elizabeth A. Eisenhauer
Phase I Cancer Clinical Trials
  • Publsiher : Unknown
  • Release : 04 October 2022
  • ISBN : 0987654321
  • Pages : 372 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Phase I Cancer Clinical Trials written by Elizabeth A. Eisenhauer which was release on 04 October 2022, this book published by Unknown. Available in PDF, EPUB and Kindle Format. Book excerpt: Phase I trials are the first step in the study of novel therapeutic approaches. They aim to identify the recommended dose, schedule and pharmacologic behavior of new drugs, and to describe the adverse effects of treatment. This practical guide discusses the design, conduct, analysis and ethical aspects of Phase I cancer trials.

Phase I Cancer Clinical Trials

Phase I Cancer Clinical Trials
  • Author : Elizabeth A. Eisenhauer,Christopher Twelves,Marc E. Buyse
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 372
  • ISBN : 0987654321
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Summary : Phase I trials are the first step in the study of novel therapeutic approaches. They aim to identify the recommended dose, schedule and pharmacologic behavior of new drugs, and to describe the adverse effects of treatment. This practical guide discusses the design, conduct, analysis and ethical aspects of Phase I ...

Handbook of Statistics in Clinical Oncology Third Edition

Handbook of Statistics in Clinical Oncology  Third Edition
  • Author : John Crowley,Antje Hoering
  • Publisher : CRC Press
  • Release Date : 2012-03-26
  • Total pages : 661
  • ISBN : 0987654321
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Summary : Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion ...

Model based Designs for Phase I Cancer Clinical Trials

Model based Designs for Phase I Cancer Clinical Trials
  • Author : Pei-Ling Chu
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 384
  • ISBN : 0987654321
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Summary : Download or read online Model based Designs for Phase I Cancer Clinical Trials written by Pei-Ling Chu, published by which was released on 2005. Get Model based Designs for Phase I Cancer Clinical Trials Books now! Available in PDF, ePub and Kindle....

Clinical Trials in Oncology

Clinical Trials in Oncology
  • Author : Stephanie Green,John Crowley,Angela Smith
  • Publisher : CRC Press
  • Release Date : 2010-12-12
  • Total pages : 281
  • ISBN : 0987654321
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Summary : Studies that are unimpeachably thorough, non-political, unbiased, and properly designed These are the standards to which everyone in clinical research aspires. Yet, the difficulties in designing trials and interpreting data are subtle and ever present. The new edition of Clinical Trials in Oncology provides a concise, nontechnical, and now...

Randomised Clinical Trials

Randomised Clinical Trials
  • Author : David Machin,Peter M. Fayers,Bee Choo Tai
  • Publisher : John Wiley & Sons
  • Release Date : 2021-08-09
  • Total pages : 560
  • ISBN : 0987654321
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Summary : Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and ...

Statistical Approaches in Oncology Clinical Development

Statistical Approaches in Oncology Clinical Development
  • Author : Satrajit Roychoudhury,Soumi Lahiri
  • Publisher : CRC Press
  • Release Date : 2018-12-07
  • Total pages : 220
  • ISBN : 0987654321
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Summary : Statistical Approaches in Oncology Clinical Development : Current Paradigm and Methodological Advancement presents an overview of statistical considerations in oncology clinical trials, both early and late phase of development. It illustrates how novel statistical methods can enrich the design and analysis of modern oncology trials. The authors include many relevant real ...

Cancer Clinical Trials

Cancer Clinical Trials
  • Author : Marc E. Buyse,Maurice J. Staquet,Maurice Staquet,Richard J. Sylvester
  • Publisher : Oxford University Press, USA
  • Release Date : 1984
  • Total pages : 506
  • ISBN : 0987654321
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Summary : The first complete guide to organizing and running cancer clinical trials, this book brings together in a single volume information on the fundamental concepts of trials, design, planning, conduct, and analysis that has previously ben scattered throughout medical and statistical literature. Topics covered include scientific background, ethical considerations, design and ...

An Iterative Phase I II I Clinical Trial Design Incorporating Genomic Biomarker Information

An Iterative Phase I II I Clinical Trial Design Incorporating Genomic Biomarker Information
  • Author : Ashok Krishnamurthy
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 448
  • ISBN : 0987654321
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Summary : The goal of a phase I cancer clinical trial is to determine the maximum tolerated dose (MTD) or the recommended phase II dose (RP2D) of a new drug that corresponds to some given acceptable rate of dose limiting toxicity. However, a common limitation to the generalizability of phase I ...

A Concise Guide to Clinical Trials

A Concise Guide to Clinical Trials
  • Author : Allan Hackshaw
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-07
  • Total pages : 224
  • ISBN : 0987654321
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Summary : Clinical trials have revolutionized the way disease is prevented, detected and treated, and early death avoided, and they continue to be an expanding area of research. They are central to the work of pharmaceutical companies, and there are many academic and public sector organizations that conduct trials on a wide ...

Fast Facts Clinical Trials in Oncology

Fast Facts  Clinical Trials in Oncology
  • Author : Allan Hackshaw,Gavin C.E. Stuart
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2020-12-18
  • Total pages : 120
  • ISBN : 0987654321
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Summary : Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are ...

Phase 1 Cancer Clinical Trials

Phase 1 Cancer Clinical Trials
  • Author : Elizabeth A. Eisenhauer,Chris Twelves,Marc E. Buyse
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0987654321
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Summary : Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. Their primary goals are to identify the recommended dose, schedule and pharmacologic behaviour of new agents or new combinations of agents and to describe the adverse effects of treatment. This comprehensive resource for oncology ...

Cancer on Trial

Cancer on Trial
  • Author : Peter Keating,Alberto Cambrosio
  • Publisher : University of Chicago Press
  • Release Date : 2011-12-25
  • Total pages : 432
  • ISBN : 0987654321
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Summary : Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, ...

Oncology Clinical Trials

Oncology Clinical Trials
  • Author : Susan Halabi, PhD,Wm. Kevin Kelly, DO
  • Publisher : Demos Medical Publishing
  • Release Date : 2009-12-22
  • Total pages : 168
  • ISBN : 0987654321
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Summary : Clinical trials are the engine of progress in the development of new drugs and devices for the detection, monitoring, prevention and treatment of cancer. A well conceived, carefully designed and efficiently conducted clinical trial can produce results that change clinical practice overnight, deliver new oncology drugs and diagnostics to the ...

Cancer Clinical Trials

Cancer Clinical Trials
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1980
  • Total pages : 212
  • ISBN : 0987654321
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Summary : Download or read online Cancer Clinical Trials written by , published by which was released on 1980. Get Cancer Clinical Trials Books now! Available in PDF, ePub and Kindle....

Phase I Cancer Clinical Trials

Phase I Cancer Clinical Trials
  • Author : Elizabeth A. Eisenhauer,Christopher Twelves,Marc Buyse
  • Publisher : Oxford University Press
  • Release Date : 2015-03-20
  • Total pages : 352
  • ISBN : 0987654321
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Summary : Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. Their primary goals are to identify the recommended dose, schedule and pharmacologic behavior of new agents or new combinations of agents and to describe the adverse effects of treatment. In cancer therapeutics, such studies ...