Patient Derived Tumor Xenograft Models

Written By Rajesh Uthamanthil
Patient Derived Tumor Xenograft Models
  • Publsiher : Academic Press
  • Release : 13 October 2016
  • ISBN : 0128040610
  • Pages : 486 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Patient Derived Tumor Xenograft Models written by Rajesh Uthamanthil which was release on 13 October 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry

Patient Derived Tumor Xenograft Models

Patient Derived Tumor Xenograft Models
  • Author : Rajesh Uthamanthil,Peggy Tinkey,Elisa de Stanchina
  • Publisher : Academic Press
  • Release Date : 2016-10-13
  • Total pages : 486
  • ISBN : 0128040610
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Summary : Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing ...

Patient Derived Xenograft Models of Human Cancer

Patient Derived Xenograft Models of Human Cancer
  • Author : Yuzhuo Wang,Dong Lin,Peter W. Gout
  • Publisher : Springer
  • Release Date : 2017-06-27
  • Total pages : 204
  • ISBN : 0128040610
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Summary : This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of ...

Patient Derived Mouse Models of Cancer

Patient Derived Mouse Models of Cancer
  • Author : Robert M. Hoffman
  • Publisher : Springer
  • Release Date : 2017-08-01
  • Total pages : 296
  • ISBN : 0128040610
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Summary : This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently ...

Colorectal Cancer Patient derived Xenograft PDX Models as Platform for Drug Screening Molecular and Response Analysis

Colorectal Cancer Patient derived Xenograft  PDX  Models as Platform for Drug Screening  Molecular and Response Analysis
  • Author : Maria Rivera
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0128040610
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Summary : Download or read online Colorectal Cancer Patient derived Xenograft PDX Models as Platform for Drug Screening Molecular and Response Analysis written by Maria Rivera, published by which was released on 2016. Get Colorectal Cancer Patient derived Xenograft PDX Models as Platform for Drug Screening Molecular and Response Analysis Books now! Available ...

From Bedside to Bench

From Bedside to Bench
  • Author : Tia Hara Turner
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 192
  • ISBN : 0128040610
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Summary : Triple-negative breast cancer (TNBC) is a clinically aggressive disease that is associated with bleak outcomes due to its metastatic propensity, frequent failure to respond to chemotherapy, and lack of alternative treatment options. Despite decades of major translational research efforts, there has been very little success thus far in the development ...

Advances in Epithelial Ovarian Cancer Model Systems Microenvironmental Influences Therapy and Origins

Advances in Epithelial Ovarian Cancer  Model Systems  Microenvironmental Influences  Therapy  and Origins
  • Author : Viive Maarika Howell,Ben Davidson,TIAN-Li WANG,Christina Annunziata
  • Publisher : Frontiers Media SA
  • Release Date : 2016-02-03
  • Total pages : 212
  • ISBN : 0128040610
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Summary : This eBook provides a compendium of the current state-of-the-art in research tools for, and understanding of, the critical research areas in epithelial ovarian cancer (EOC) with a strong emphasis on (HG-SOC). Research areas covered include therapy response and development, microenvironmental influences and the etiology and progression of EOC. Ten articles ...

Tumor Models in Cancer Research

Tumor Models in Cancer Research
  • Author : Beverly A. Teicher
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-12-01
  • Total pages : 693
  • ISBN : 0128040610
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Summary : The past 6 years since the first edition of this book have seen great progress in the development of genetically engineered mouse (GEM) models of cancer. These models are finding an important role in furthering our understanding of the biology of malignant disease. A comfortable position for GEM models in the ...

Differential Antitumor Activity of Aflibercept and Bevacizumab in Patient derived Xenograft Models of Colorectal Cancer

Differential Antitumor Activity of Aflibercept and Bevacizumab in Patient derived Xenograft Models of Colorectal Cancer
  • Author : Marielle Chiron
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 9
  • ISBN : 0128040610
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Summary : Download or read online Differential Antitumor Activity of Aflibercept and Bevacizumab in Patient derived Xenograft Models of Colorectal Cancer written by Marielle Chiron, published by which was released on 2014. Get Differential Antitumor Activity of Aflibercept and Bevacizumab in Patient derived Xenograft Models of Colorectal Cancer Books now! Available in PDF, ...

Translational Research in Breast Cancer

Translational Research in Breast Cancer
  • Author : Dong-Young Noh,Wonshik Han,Masakazu Toi
  • Publisher : Springer Nature
  • Release Date : 2021-05-13
  • Total pages : 630
  • ISBN : 0128040610
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Summary : This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as ...

Molecular Diagnosis and Targeting for Gynecologic Malignancy

Molecular Diagnosis and Targeting for Gynecologic Malignancy
  • Author : Seiji Isonishi,Yoshihiro Kikuchi
  • Publisher : Springer Nature
  • Release Date : 2021-03-05
  • Total pages : 165
  • ISBN : 0128040610
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Summary : This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding ...

Animal Models in Cancer Drug Discovery

Animal Models in Cancer Drug Discovery
  • Author : Asfar Azmi,Ramzi M. Mohammad
  • Publisher : Academic Press
  • Release Date : 2019-04-16
  • Total pages : 470
  • ISBN : 0128040610
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Summary : Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on ...

Nanotechnology Applications for Cancer Chemotherapy

Nanotechnology Applications for Cancer Chemotherapy
  • Author : Sanyog Jain,Kaisar Raza,Ashish Kumar Agrawal,Ankur Vaidya
  • Publisher : Elsevier
  • Release Date : 2020-09-30
  • Total pages : 702
  • ISBN : 0128040610
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Summary : Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses ...

Advances in Radiation Therapy

Advances in Radiation Therapy
  • Author : M. Guckenberger,S.E. Combs,D. Zips
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2018-04-12
  • Total pages : 134
  • ISBN : 0128040610
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Summary : Developments in radiation oncology have been key to the tremendous progress made in the field in recent years. The combination of optimal systemic treatment and local therapy has resulted in continuing improved outcomes of cancer therapy. This progress forms the basis for current pre-clinical and clinical research which will strengthen ...

Bioinformatics Analysis of Single Cell Sequencing Data and Applications in Precision Medicine

Bioinformatics Analysis of Single Cell Sequencing Data and Applications in Precision Medicine
  • Author : Jialiang Yang,Liao Bo,Tuo Zhang,Yifei Xu
  • Publisher : Frontiers Media SA
  • Release Date : 2020-02-27
  • Total pages : 212
  • ISBN : 0128040610
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Summary : Download or read online Bioinformatics Analysis of Single Cell Sequencing Data and Applications in Precision Medicine written by Jialiang Yang,Liao Bo,Tuo Zhang,Yifei Xu, published by Frontiers Media SA which was released on 2020-02-27. Get Bioinformatics Analysis of Single Cell Sequencing Data and Applications in Precision Medicine ...

Topics in Anti Cancer Research Volume 10

Topics in Anti Cancer Research  Volume 10
  • Author : Atta-ur-Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2021-12-13
  • Total pages : 170
  • ISBN : 0128040610
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Summary : Topics in Anti-Cancer Research covers new developments in the field of cancer diagnosis and drug therapy. Novel drugs as anticancer agents include natural and synthetic phenazirines and other anti-cancer compounds. The series also covers information on the current understanding of the pathology and molecular biology of specific neoplasms. The diversity ...