New Approaches of Protein Function Prediction from Protein Interaction Networks

Written By Jingyu Hou
New Approaches of Protein Function Prediction from Protein Interaction Networks
  • Publsiher : Academic Press
  • Release : 15 January 2017
  • ISBN : 9780128098141
  • Pages : 124 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled New Approaches of Protein Function Prediction from Protein Interaction Networks written by Jingyu Hou which was release on 15 January 2017, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction. Provides innovative approaches and new developments targeting key issues in protein function prediction Presents heuristic ideas for further research in this challenging area

New Approaches of Protein Function Prediction from Protein Interaction Networks

New Approaches of Protein Function Prediction from Protein Interaction Networks
  • Author : Jingyu Hou
  • Publisher : Academic Press
  • Release Date : 2017-01-15
  • Total pages : 124
  • ISBN : 9780128098141
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Summary : New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins ...

New Approaches of Protein Function Prediction from Protein Interaction Networks

New Approaches of Protein Function Prediction from Protein Interaction Networks
  • Author : Jingyu Hou
  • Publisher : Academic Press
  • Release Date : 2017-01-13
  • Total pages : 124
  • ISBN : 9780128098141
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Summary : New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins ...

Protein Function Prediction from Protein Interaction Network

Protein Function Prediction from Protein Interaction Network
  • Author : Sovan Saha,Piyali Chatterjee
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2013
  • Total pages : 148
  • ISBN : 9780128098141
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Summary : Proteins perform every function in a cell. With the advent of genome sequencing projects for different organisms, large amounts of DNA and protein sequence data is available, whereas their biological function is still unknown in the most of the cases. Predicting protein function is the most challenging problem in post-genomic ...

Functional Module Identification and Function Prediction from Protein Interaction Networks

Functional Module Identification and Function Prediction from Protein Interaction Networks
  • Author : Young-Rae Cho
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 179
  • ISBN : 9780128098141
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Summary : Since the completion of sequencing human genome, uncovering the principles of interactions and the functional roles of proteins has been in the spotlight in this post-genomic era. The interactions between proteins provide insights into the underlying mechanisms of biological processes within a cell. The functions of an unknown protein can ...

Protein protein Interactions and Networks

Protein protein Interactions and Networks
  • Author : Anna Panchenko,Teresa M. Przytycka
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-04-06
  • Total pages : 212
  • ISBN : 9780128098141
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Summary : The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse ...

Protein Interaction Networks in Health and Disease

Protein Interaction Networks in Health and Disease
  • Author : Spyros Petrakis,Miguel A. Andrade-Navarro
  • Publisher : Frontiers Media SA
  • Release Date : 2016-10-19
  • Total pages : 212
  • ISBN : 9780128098141
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Summary : The identification and mapping of protein-protein interactions (PPIs) is a major goal in systems biology. Experimental data are currently produced in large scale using a variety of high-throughput assays in yeast or mammalian systems. Analysis of these data using computational tools leads to the construction of large protein interaction networks, ...

Development and Application of a Computational Approach to Align Protein Interaction Networks

Development and Application of a Computational Approach to Align Protein Interaction Networks
  • Author : Phan Thi Thu Hang,Michael Sternberg
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 9780128098141
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Summary : This thesis describes the development of PINALOG, a protein interaction network alignment method, and its application to the area of protein function prediction and protein complex detection. Protein-protein interactions (PPI) play an important role in the function of biological processes. Advances in high-throughput technology have produced a large amount of ...

Biomolecular Networks

Biomolecular Networks
  • Author : Luonan Chen,Rui-Sheng Wang,Xiang-Sun Zhang
  • Publisher : John Wiley & Sons
  • Release Date : 2009-06-29
  • Total pages : 416
  • ISBN : 9780128098141
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Summary : Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living ...

Phylogenetic Approaches to Protein Function Prediction and Protein Network Analysis

Phylogenetic Approaches to Protein Function Prediction and Protein Network Analysis
  • Author : Jie Wu
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 298
  • ISBN : 9780128098141
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Summary : Abstract: One of the defining challenges in the post-genomic era is to develop computational and experimental tools to elucidate the mechanisms of bio-molecular interactions within the cell and between the cell and environment. The recent availability of an increasing number of completely sequenced genomes from diverse species has opened new ...

Data Management of Protein Interaction Networks

Data Management of Protein Interaction Networks
  • Author : Mario Cannataro,Pietro H. Guzzi
  • Publisher : John Wiley & Sons
  • Release Date : 2012-02-03
  • Total pages : 300
  • ISBN : 9780128098141
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Summary : Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described ...

Protein Protein Interactions

Protein Protein Interactions
  • Author : Weibo Cai,Hao Hong
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-03-30
  • Total pages : 486
  • ISBN : 9780128098141
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Summary : Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays ...

Systems Biology

Systems Biology
  • Author : Aleš Prokop,Béla Csukás
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-08-28
  • Total pages : 553
  • ISBN : 9780128098141
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Summary : Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent ...

Prediction of Protein Structures Functions and Interactions

Prediction of Protein Structures  Functions  and Interactions
  • Author : Janusz M. Bujnicki
  • Publisher : John Wiley & Sons
  • Release Date : 2008-12-23
  • Total pages : 302
  • ISBN : 9780128098141
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Summary : The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of ...

Protein Function Prediction for Omics Era

Protein Function Prediction for Omics Era
  • Author : Daisuke Kihara
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-04-19
  • Total pages : 310
  • ISBN : 9780128098141
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Summary : Gene function annotation has been a central question in molecular biology. The importance of computational function prediction is increasing because more and more large scale biological data, including genome sequences, protein structures, protein-protein interaction data, microarray expression data, and mass spectrometry data, are awaiting biological interpretation. Traditionally when a genome ...

Genome Wide Prediction and Analysis of Protein Protein Functional Linkages in Bacteria

Genome Wide Prediction and Analysis of Protein Protein Functional Linkages in Bacteria
  • Author : Vijaykumar Yogesh Muley,Vishal Acharya
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-07-28
  • Total pages : 60
  • ISBN : 9780128098141
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Summary : ​​ ​Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics ...