Mitochondria and Brain Disorders

Written By Stavros Baloyannis
Mitochondria and Brain Disorders
  • Publsiher : BoD – Books on Demand
  • Release : 11 March 2020
  • ISBN : 1789855314
  • Pages : 124 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Mitochondria and Brain Disorders written by Stavros Baloyannis which was release on 11 March 2020, this book published by BoD – Books on Demand. Available in PDF, EPUB and Kindle Format. Book excerpt: The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

Mitochondria and Brain Disorders

Mitochondria and Brain Disorders
  • Author : Stavros Baloyannis
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-03-11
  • Total pages : 124
  • ISBN : 1789855314
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Summary : The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity ...

Mitochondria in Neurological Disorders

Mitochondria in Neurological Disorders
  • Author : Rajat Sandhir
  • Publisher : Academic Press
  • Release Date : 2021-12-01
  • Total pages : 500
  • ISBN : 1789855314
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Summary : Mitochondria in Neurological Diseases highlights various therapeutic approaches targeting mitochondria in neurological conditions. Focused on diverse neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, depression, and Amyotrophic lateral sclerosis, topics span basic mitochondrial physiology to mitochondrial dynamics and to the altered states of the nervous ...

The Functions Disease Related Dysfunctions and Therapeutic Targeting of Neuronal Mitochondria

The Functions  Disease Related Dysfunctions  and Therapeutic Targeting of Neuronal Mitochondria
  • Author : J. Marie Hardwick
  • Publisher : John Wiley & Sons
  • Release Date : 2015-11-09
  • Total pages : 448
  • ISBN : 1789855314
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Summary : This book focuses on dysfunctional neuronal mitochondria, their functions, cell pathways, and properties and how they relate to therapeutics and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases. ...

Mitochondrial Dysfunction in Neurodegenerative Disorders

Mitochondrial Dysfunction in Neurodegenerative Disorders
  • Author : Amy Katherine Reeve,Kim Jennifer Krishnan,Michael R. Duchen,Doug M Turnbull
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-11-15
  • Total pages : 242
  • ISBN : 1789855314
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Summary : As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple ...

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-05-16
  • Total pages : 260
  • ISBN : 1789855314
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Summary : Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this ...

Role of Mitochondria in Neurological Disease

Role of Mitochondria in Neurological Disease
  • Author : Anthony S. Basile
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 118
  • ISBN : 1789855314
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Summary : Download or read online Role of Mitochondria in Neurological Disease written by Anthony S. Basile, published by which was released on 2002. Get Role of Mitochondria in Neurological Disease Books now! Available in PDF, ePub and Kindle....

Pharmacology of Mitochondria

Pharmacology of Mitochondria
  • Author : Harpreet Singh,Shey-Shing Sheu
  • Publisher : Springer
  • Release Date : 2017-08-11
  • Total pages : 493
  • ISBN : 1789855314
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Summary : This special book is conceived to highlight mitochondrial structural and functional integrity and how they are associated with several human diseases such as cardiovascular, cancer, renal, neurological disorder, and genetic disorders. The chapters contributed by leading mitochondrial researchers in the handbook will take us through the novel pharmacological strategies via ...

Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration

Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration
  • Author : Hao Chen
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 212
  • ISBN : 1789855314
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Summary : Mitochondria are critical regulators of neuronal physiology. They play a pivotal role in energy supply and Ca2+ buffering. Thus, mitochondria can sustain the synapse and neuronal function. In this regard, the mitochondria with an impaired capacity of bioenergetics or Ca2+ buffering will lead to synapse failure and neurodegeneration. Moreover, emerging ...

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer
  • Release Date : 2013-01-02
  • Total pages : 260
  • ISBN : 1789855314
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Summary : Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this ...

Mitochondrial Myopathies

Mitochondrial Myopathies
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 1789855314
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Summary : Download or read online Mitochondrial Myopathies written by , published by which was released on 2007. Get Mitochondrial Myopathies Books now! Available in PDF, ePub and Kindle....

Mitochondria and the Future of Medicine

Mitochondria and the Future of Medicine
  • Author : Lee Know
  • Publisher : Chelsea Green Publishing
  • Release Date : 2018-02-19
  • Total pages : 272
  • ISBN : 1789855314
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Summary : With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? ...

Interactions Between the Ubiquitin Proteasome System and Mitochondria in Ageing and Neurological Disorders

Interactions Between the Ubiquitin Proteasome System and Mitochondria in Ageing and Neurological Disorders
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 316
  • ISBN : 1789855314
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Summary : Download or read online Interactions Between the Ubiquitin Proteasome System and Mitochondria in Ageing and Neurological Disorders written by , published by which was released on 2015. Get Interactions Between the Ubiquitin Proteasome System and Mitochondria in Ageing and Neurological Disorders Books now! Available in PDF, ePub and Kindle....

Molecular Basis of Neurological Disorders and Their Treatment

Molecular Basis of Neurological Disorders and Their Treatment
  • Author : J.W. Gorrod,A. Albano,E. Ferrari,S. Papa
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 337
  • ISBN : 1789855314
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Summary : cytochemical techniques (ICC) which provide a useful adjunct to investigations by immunoblotting. A particular advantage of a cytochemical approach to the investiga tion of mitochondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza tion involved in conventional enzyme ...

Mitochondrial Disorders in Neurology

Mitochondrial Disorders in Neurology
  • Author : Anthony H.V. Schapira,S. Dimauro
  • Publisher : Butterworth-Heinemann
  • Release Date : 2013-10-22
  • Total pages : 264
  • ISBN : 1789855314
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Summary : Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise ...

Metabolic Syndrome and Neurological Disorders

Metabolic Syndrome and Neurological Disorders
  • Author : Akhlaq A. Farooqui,Tahira Farooqui
  • Publisher : John Wiley & Sons
  • Release Date : 2013-09-26
  • Total pages : 576
  • ISBN : 1789855314
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Summary : Metabolic Syndrome and Neurological Disorders brings together information on the cluster of common pathologies which cause metabolic syndrome - abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension - to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological ...