Microfluidic Cell Culture Systems

Written By Jeffrey T Borenstein
Microfluidic Cell Culture Systems
  • Publsiher : Elsevier
  • Release : 12 September 2018
  • ISBN : 0128136723
  • Pages : 396 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Microfluidic Cell Culture Systems written by Jeffrey T Borenstein which was release on 12 September 2018, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques are well-suited to the size scale of biological cells. Microfluidic Cell Culture Systems applies design and experimental techniques used in in microfluidics, and cell culture technologies to organ-on-chip systems. This book is intended to serve as a professional reference, providing a practical guide to design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and human organ models. The book covers topics ranging from academic first principles of microfluidic design, to clinical translation strategies for cell culture protocols. The goal is to help professionals coming from an engineering background to adapt their expertise for use in cell culture and organ models applications, and likewise to help biologists to design and employ microfluidic technologies in their cell culture systems. This 2nd edition contains new material that strengthens the focus on in vitro models useful for drug discovery and development. One new chapter reviews liver organ models from an industry perspective, while others cover new technologies for scaling these models and for multi-organ systems. Other new chapters highlight the development of organ models and systems for specific applications in disease modeling and drug safety. Previous chapters have been revised to reflect the latest advances. Provides design and operation methodology for microfluidic and microfabricated materials and devices for organ-on-chip disease and safety models. This is a rapidly expanding field that will continue to grow along with advances in cell biology and microfluidics technologies. Comprehensively covers strategies and techniques ranging from academic first principles to industrial scale-up approaches. Readers will gain insight into cell-material interactions, microfluidic flow, and design principles. Offers three fundamental types of information: 1) design principles, 2) operation techniques, and 3) background information/perspectives. The book is carefully designed to strike a balance between these three areas, so it will be of use to a broad range of readers with different technical interests and educational levels.

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
  • Author : Jeffrey T Borenstein,Vishal Tandon,Sarah L Tao,Joseph L. Charest
  • Publisher : Elsevier
  • Release Date : 2018-09-12
  • Total pages : 396
  • ISBN : 0128136723
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Summary : Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques ...

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
  • Author : Christopher Bettinger,Jeffrey T Borenstein,Sarah L Tao
  • Publisher : William Andrew
  • Release Date : 2012-12-31
  • Total pages : 452
  • ISBN : 0128136723
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Summary : The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an ...

Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses

Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses
  • Author : Tino Frank
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Download or read online Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses written by Tino Frank, published by which was released on 2016. Get Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses Books now! Available in PDF, ePub and Kindle....

Microfluidics Based Microsystems

Microfluidics Based Microsystems
  • Author : S. Kakaç,B. Kosoy,D. Li,A. Pramuanjaroenkij
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-09-10
  • Total pages : 618
  • ISBN : 0128136723
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Summary : This volume contains an archival record of the NATO Advanced Study Institute on Microfluidics Based Microsystems – Fundamentals and App- cations held in Çe ?me-Izmir, Turkey, August 23–September 4, 2009. ASIs are intended to be high-level teaching activity in scientific and technical areas of current concern. In this volume, the reader may find ...

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip Advances in Organs on a Chip and Organoids Technologies

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip  Advances in Organs on a Chip and Organoids Technologies
  • Author : Qasem Ramadan,Massimo Alberti,Martin Dufva,Yi-Chung Tung
  • Publisher : Frontiers Media SA
  • Release Date : 2019-10-16
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific ...

Multiplexed Microfabricated Cell Culture Device for Stem Cell Process Development

Multiplexed Microfabricated Cell Culture Device for Stem Cell Process Development
  • Author : M. Reichen
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 0128136723
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Summary : In this thesis, a multiplexed micro-fabricated cell culture device is presented to probe the soluble micro-environment of stem cells. A large number of biological, physical and chemical variables determine the micro-environment of stem cells and affect therefore their fate. The soluble micro-environment is believed to play a pivotal role in ...

Microfluidics in Cell BiologyPart A Microfluidics for multicellular systems

Microfluidics in Cell BiologyPart A  Microfluidics for multicellular systems
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-07-20
  • Total pages : 273
  • ISBN : 0128136723
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Summary : Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids, Collective migration in microtubes, Leukocyte adhesion ...

Cell Analysis on Microfluidics

Cell Analysis on Microfluidics
  • Author : Jin-Ming Lin
  • Publisher : Springer
  • Release Date : 2017-10-25
  • Total pages : 429
  • ISBN : 0128136723
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Summary : This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in ...

Microfluidic Organ on a Chip Revolutionary Platforms for Disease Comprehension and Treatment

Microfluidic Organ on a Chip  Revolutionary Platforms for Disease Comprehension and Treatment
  • Author : Shi-Cong Tao,Shang-Chun Guo,Wei Seong Toh,Nuno M. Neves,Owen Gareth Davies
  • Publisher : Frontiers Media SA
  • Release Date : 2022-01-11
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Existing culture systems have a limited ability to reproduce the complicated and dynamic microenvironment of a functioning organ. To solve the issues of conventional culture techniques, multidisciplinary researchers, involving medical doctors, stem cell and developmental biology experts, engineers and physical scientists, have emerged to innovate methods and devices. A microfluidic ...

Animal Biotechnology

Animal Biotechnology
  • Author : Ashish S. Verma,Anchal Singh
  • Publisher : Academic Press
  • Release Date : 2020-07-03
  • Total pages : 798
  • ISBN : 0128136723
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Summary : Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ...

Cardiac Cell Culture Technologies

Cardiac Cell Culture Technologies
  • Author : Zbigniew Brzozka,Elzbieta Jastrzebska
  • Publisher : Springer
  • Release Date : 2017-11-21
  • Total pages : 234
  • ISBN : 0128136723
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Summary : This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center ...

Microfluidic Technologies for Human Health

Microfluidic Technologies for Human Health
  • Author : Utkan Demirci,Robert Langer
  • Publisher : World Scientific
  • Release Date : 2012
  • Total pages : 478
  • ISBN : 0128136723
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Summary : The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves steps from biological sample/analyte loading to ...

Nanobiomaterials

Nanobiomaterials
  • Author : Dong Yi,Georgia C. Papaefthymiou
  • Publisher : CRC Press
  • Release Date : 2013-08-14
  • Total pages : 490
  • ISBN : 0128136723
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Summary : There is a continuous exchange of ideas taking place at the border of the biological and physical sciences in many areas of nanoscience. Nanotechnology uses biomimetic or bio-inspired processes to produce nanosized materials for applications in biology and other fields. In return, the fruits of nanotechnology are applied to expanding ...

Microfluidic Methods for Molecular Biology

Microfluidic Methods for Molecular Biology
  • Author : Chang Lu,Scott S. Verbridge
  • Publisher : Springer
  • Release Date : 2016-05-14
  • Total pages : 376
  • ISBN : 0128136723
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Summary : This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology ...

Recent Advances in Cytometry Part A

Recent Advances in Cytometry  Part A
  • Author : Zbigniew Darzynkiewicz,Elena Holden,Alberto Orfao,William Telford,Donald Wlodkowic
  • Publisher : Academic Press
  • Release Date : 2011-06-15
  • Total pages : 579
  • ISBN : 0128136723
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Summary : Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. ...