Handbook of Pharmacogenomics and Stratified Medicine

Written By Sandosh Padmanabhan
Handbook of Pharmacogenomics and Stratified Medicine
  • Publsiher : Academic Press
  • Release : 28 April 2014
  • ISBN : 0123868831
  • Pages : 1118 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Handbook of Pharmacogenomics and Stratified Medicine written by Sandosh Padmanabhan which was release on 28 April 2014, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details. Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics Covers newer technologies– next generation sequencing, proteomics, metabolomics Provides information on animal models, lymphoblastoid cell lines, stem cells Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues Includes chapters on the global implications of pharmacogenomics

Handbook of Pharmacogenomics and Stratified Medicine

Handbook of Pharmacogenomics and Stratified Medicine
  • Author : Sandosh Padmanabhan
  • Publisher : Academic Press
  • Release Date : 2014-04-28
  • Total pages : 1118
  • ISBN : 0123868831
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Summary : Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic ...

Handbook of Personalized Medicine

Handbook of Personalized Medicine
  • Author : Ioannis S. Vizirianakis
  • Publisher : CRC Press
  • Release Date : 2014-02-12
  • Total pages : 1560
  • ISBN : 0123868831
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Summary : This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational ...

Handbook of Biomarkers and Precision Medicine

Handbook of Biomarkers and Precision Medicine
  • Author : Claudio Carini,Mark Fidock,Alain van Gool
  • Publisher : CRC Press
  • Release Date : 2019-04-16
  • Total pages : 631
  • ISBN : 0123868831
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Summary : "The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge ...

Handbook of Personalized Medicine

Handbook of Personalized Medicine
  • Author : Ioannis S. Vizirianakis
  • Publisher : CRC Press
  • Release Date : 2014-02-12
  • Total pages : 1560
  • ISBN : 0123868831
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Summary : This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational ...

Pharmacoepigenetics

Pharmacoepigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-06-04
  • Total pages : 983
  • ISBN : 0123868831
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Summary : Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the ...

Handbook of Drug Monitoring Methods

Handbook of Drug Monitoring Methods
  • Author : Amitava Dasgupta
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-10-23
  • Total pages : 445
  • ISBN : 0123868831
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Summary : In Handbook of Drug Monitoring Methods: Therapeutics and Drug Abuse, authors discuss the different analytical techniques used in today’s practice of therapeutic drug monitoring and drugs of abuse as well as alcohol testing with relevant theory, mechanism, and in-depth scientific discussion on each topic. This volume is the perfect ...

Pharmacogenomics and Precision Medicine An Issue of the Clinics in Laboratory Medicine E Book

Pharmacogenomics and Precision Medicine  An Issue of the Clinics in Laboratory Medicine  E Book
  • Author : Kristen Reynolds,Roland Valdes
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-08-16
  • Total pages : 177
  • ISBN : 0123868831
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Summary : This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, ...

Handbook of Children s Rights

Handbook of Children s Rights
  • Author : Martin D. Ruck,Michele Peterson-Badali,Michael Freeman
  • Publisher : Taylor & Francis
  • Release Date : 2016-12-08
  • Total pages : 618
  • ISBN : 0123868831
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Summary : While the notion of young people as individuals worthy or capable of having rights is of relatively recent origin, over the past several decades there has been a substantial increase in both social and political commitment to children’s rights as well as a tendency to grant young people some ...

Personalized Psychiatry

Personalized Psychiatry
  • Author : Bernhard Baune
  • Publisher : Academic Press
  • Release Date : 2019-10-16
  • Total pages : 604
  • ISBN : 0123868831
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Summary : Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important ...

The Oxford Handbook of Substance Use and Substance Use Disorders

The Oxford Handbook of Substance Use and Substance Use Disorders
  • Author : Kenneth J. Sher
  • Publisher : Oxford University Press
  • Release Date : 2016-06-29
  • Total pages : 768
  • ISBN : 0123868831
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Summary : Substance use and substance use disorders (SUDs) have been documented in a number of cultures since the beginnings of recorded time and represent major societal concerns in the present day. The Oxford Handbook of Substance Use and Substance Use Disorders provides comprehensive reviews of key areas of inquiry into the ...

Mastering Pharmacogenomics A Nurse s Handbook for Success

Mastering Pharmacogenomics  A Nurse s Handbook for Success
  • Author : Dale Halsey Lea,Dennis J. Cheek,Daniel Brazeau,Gayle Brazeau
  • Publisher : Sigma Theta Tau
  • Release Date : 2015-01-14
  • Total pages : 264
  • ISBN : 0123868831
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Summary : Pharmacogenomics, the study of the role of genetics in drug response, has developed into a critical new area in battling disease and improving outcomes. As our knowledge of the human genome grows, and with the advent of next-generation sequencing technologies, the role of genetic research is evolving to guide therapy ...

Preclinical Development Handbook

Preclinical Development Handbook
  • Author : Shayne Cox Gad
  • Publisher : Wiley-Interscience
  • Release Date : 2008-03-14
  • Total pages : 1080
  • ISBN : 0123868831
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Summary : A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use ...

Socio economics of Personalized Medicine in Asia

Socio economics of Personalized Medicine in Asia
  • Author : Shirley Sun
  • Publisher : Routledge
  • Release Date : 2016-07-01
  • Total pages : 198
  • ISBN : 0123868831
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Summary : The second decade of the twenty-first century has witnessed a surging interest in personalized medicine with the concomitant promise to enable more precise diagnosis and treatment of disease and illness, based upon an individual’s unique genetic makeup. In this book, my goal is to contribute to a growing body ...

Handbook of Pharmaceutical Biotechnology

Handbook of Pharmaceutical Biotechnology
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2007-05-25
  • Total pages : 1680
  • ISBN : 0123868831
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Summary : A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in ...

Drug Design

Drug Design
  • Author : Arli Aditya Parikesit
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-06-16
  • Total pages : 159
  • ISBN : 0123868831
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Summary : Right before the COVID-19 pandemic declared by the World Health Organization (WHO), life sciences have incited novel areas of studies that revolutionize the health sector. They are the studies of structural bioinformatics, pharmacogenomics, and metabolomics. The structural bioinformatics field is the very foundation of drug design research, as it provides ...