Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Written By G V Sherbet
Growth Factors and Their Receptors in Cell Differentiation  Cancer and Cancer Therapy
  • Publsiher : Elsevier
  • Release : 12 July 2011
  • ISBN : 0123878209
  • Pages : 368 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKGrowth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy


Read or download book entitled Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy written by G V Sherbet which was release on 12 July 2011, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes Aids the development of therapeutic treatments for cancer Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research

Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation  Cancer and Cancer Therapy
  • Author : G V Sherbet
  • Publisher : Elsevier
  • Release Date : 2011-07-12
  • Total pages : 368
  • ISBN : 0123878209
GET BOOK

Summary : Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. ...

Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation  Cancer and Cancer Therapy
  • Author : Gajanan V. Sherbet
  • Publisher : Unknown
  • Release Date : 2011-07-28
  • Total pages : 368
  • ISBN : 0123878209
GET BOOK

Summary : Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. ...

Growth Factors and their Receptors in Cancer Metastasis

Growth Factors and their Receptors in Cancer Metastasis
  • Author : Wen G. Jiang,K. Matsumoto,T. Nakamura
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-04-11
  • Total pages : 303
  • ISBN : 0123878209
GET BOOK

Summary : about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem ...

Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation  Cancer and Cancer Therapy
  • Author : Gajanan V. Sherbet
  • Publisher : Elsevier
  • Release Date : 2011
  • Total pages : 347
  • ISBN : 0123878209
GET BOOK

Summary : Annotation G.V. Sherbet provides insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. The book focuses on the relationships and convergence of growth factors and their receptors in development and pathogenesis....

Therapeutic Strategies in Cancer Biology and Pathology

Therapeutic Strategies in Cancer Biology and Pathology
  • Author : Gajanan V. Sherbet
  • Publisher : Elsevier
  • Release Date : 2013-07-26
  • Total pages : 310
  • ISBN : 0123878209
GET BOOK

Summary : Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, ...

The Genetics of Cancer

The Genetics of Cancer
  • Author : Gajanan V. Sherbet,M. S. Lakshmi
  • Publisher : Academic Press
  • Release Date : 1997-06-22
  • Total pages : 338
  • ISBN : 0123878209
GET BOOK

Summary : Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor ...

Genetic Recombination in Cancer

Genetic Recombination in Cancer
  • Author : Gajanan V. Sherbet
  • Publisher : Elsevier
  • Release Date : 2003-07-24
  • Total pages : 264
  • ISBN : 0123878209
GET BOOK

Summary : Genetic recombination is a process of combining genes that leads to the generation of cell variants that possess different characteristics. This process is important to the evolution of a species and to embryonic growth and differentiation. However, this process can also lead to the development of abnormal, cancerous cells. This ...

Insulin Like Growth Factors

Insulin Like Growth Factors
  • Author : Douglas Yee
  • Publisher : IOS Press
  • Release Date : 2003
  • Total pages : 124
  • ISBN : 0123878209
GET BOOK

Summary : Over the past five years there has been an explosion of "targeted therapies" for cancer treatment. In most cases, these therapies have been based on pre-clinical data showing that specific molecules play an important role in regulating the malignant phenotype. In breast cancer, there is compelling rationale that such targeted ...

Molecular Approach to Cancer Management

Molecular Approach to Cancer Management
  • Author : Gajanan V. Sherbet
  • Publisher : Academic Press
  • Release Date : 2017-06-15
  • Total pages : 352
  • ISBN : 0123878209
GET BOOK

Summary : Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the ...

Fibroblast Growth Factors Biology And Clinical Application Fgf Biology And Therapeutics

Fibroblast Growth Factors  Biology And Clinical Application   Fgf Biology And Therapeutics
  • Author : Simons Michael
  • Publisher : World Scientific
  • Release Date : 2016-12-27
  • Total pages : 284
  • ISBN : 0123878209
GET BOOK

Summary : The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and ...

Blood Cell Biochemistry

Blood Cell Biochemistry
  • Author : Anthony D. Whetton,John Gordon
  • Publisher : Springer Science & Business Media
  • Release Date : 1996-08-31
  • Total pages : 419
  • ISBN : 0123878209
GET BOOK

Summary : Volume 7 explores the role of receptors and growth factors in the control of hematopoiesis and the immune system. This work features color plates and numerous illustrations....

Insulin like Growth Factor Receptor Signalling

Insulin like Growth Factor Receptor Signalling
  • Author : Derek Leroith,Walter Zumkeller,Robert C. Baxter
  • Publisher : Springer Science & Business Media
  • Release Date : 2003-07-31
  • Total pages : 524
  • ISBN : 0123878209
GET BOOK

Summary : Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its significance in growth and development, the insulin-like ...

The Effects of Insulin Like Growth Factors on Human G292 Osteosarcoma Cells

The Effects of Insulin Like Growth Factors on Human G292 Osteosarcoma Cells
  • Author : Thabet AlHousami
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 0123878209
GET BOOK

Summary : Introduction: Osteosarcoma is the most common bone sarcoma in children and adolescents. It is an aggressive primary bone cancer recognized by abnormal cell proliferation and function. The insulin-like growth factor (IGF) system plays an integral role in the growth, differentiation, and developmental processes, and is involved in various physiological and ...

Growth Factors and Their Receptors

Growth Factors and Their Receptors
  • Author : Russell Ross,Antony Burgess,Tony Hunter
  • Publisher : Alan R. Liss
  • Release Date : 1989
  • Total pages : 319
  • ISBN : 0123878209
GET BOOK

Summary : Download or read online Growth Factors and Their Receptors written by Russell Ross,Antony Burgess,Tony Hunter, published by Alan R. Liss which was released on 1989. Get Growth Factors and Their Receptors Books now! Available in PDF, ePub and Kindle....

EGFR Signaling Networks in Cancer Therapy

EGFR Signaling Networks in Cancer Therapy
  • Author : John D. Haley,William John Gullick
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-03-01
  • Total pages : 395
  • ISBN : 0123878209
GET BOOK

Summary : The epidermal gro wth factor (EGF ) receptor and its downstream signal transduction networks have been implicated in the ontology and maintenance of tumor tissues, which has motivated the discovery and development of molecularly targeted anti-EGF receptor therapies. Over decades of study, the EGF receptor structure, its ligand binding domains, the ...