Genome Stability

Written By Igor Kovalchuk
Genome Stability
  • Publsiher : Academic Press
  • Release : 17 July 2021
  • ISBN : 0323856802
  • Pages : 760 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Genome Stability written by Igor Kovalchuk which was release on 17 July 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability Contains applications of genome instability research and outcomes for human disease Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair

Genome Stability

Genome Stability
  • Author : Igor Kovalchuk,Olga Kovalchuk
  • Publisher : Academic Press
  • Release Date : 2021-07-17
  • Total pages : 760
  • ISBN : 0323856802
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Summary : Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single ...

Genome Stability and Human Diseases

Genome Stability and Human Diseases
  • Author : Heinz-Peter Nasheuer
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-12-11
  • Total pages : 340
  • ISBN : 0323856802
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Summary : Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the ...

Genome Stability

Genome Stability
  • Author : James Haber
  • Publisher : Garland Science
  • Release Date : 2013-12-16
  • Total pages : 416
  • ISBN : 0323856802
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Summary : Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An...

Nuclear Genome Stability DNA Replication Telomere Maintenance and DNA Repair

Nuclear Genome Stability  DNA Replication  Telomere Maintenance  and DNA Repair
  • Author : Maria Isabel Nogueira Cano,Richard McCulloch,Marcelo Santos Da Silva
  • Publisher : Frontiers Media SA
  • Release Date : 2022-03-09
  • Total pages : 212
  • ISBN : 0323856802
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Summary : Download or read online Nuclear Genome Stability DNA Replication Telomere Maintenance and DNA Repair written by Maria Isabel Nogueira Cano,Richard McCulloch,Marcelo Santos Da Silva, published by Frontiers Media SA which was released on 2022-03-09. Get Nuclear Genome Stability DNA Replication Telomere Maintenance and DNA Repair Books now! ...

Mobile Genetic Elements in Cellular Differentiation Genome Stability and Cancer

Mobile Genetic Elements in Cellular Differentiation  Genome Stability  and Cancer
  • Author : Tammy A. Morrish,Jose Luis García Pérez
  • Publisher : Frontiers Media SA
  • Release Date : 2018-01-16
  • Total pages : 212
  • ISBN : 0323856802
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Summary : The human genome, as with the genome of most organisms, is comprised of various types of mobile genetic element derived repeats. Mobile genetic elements that mobilize by an RNA intermediate, include both autonomous and non-autonomous retrotransposons, and mobilize by a “copy and paste” mechanism that relies of the presence of ...

Genome Instability in Cancer Development

Genome Instability in Cancer Development
  • Author : Erich A. Nigg
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-01-14
  • Total pages : 512
  • ISBN : 0323856802
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Summary : Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These important findings not only explain the occurrence of certain ...

Roles for the Saccharomyces Cerevisiae MLH1 Mismatch Repair Gene in Genome Stability and Genetic Recombination

Roles for the Saccharomyces Cerevisiae MLH1 Mismatch Repair Gene in Genome Stability and Genetic Recombination
  • Author : Juan Argueso Almeida
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 296
  • ISBN : 0323856802
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Summary : Mismatch repair (MMR) systems correct mismatches formed during DNA replication and genetic recombination and as the result of DNA damage. MMR is initiated by a conserved family of MutS (MSH) and MutL (MLH) homolog proteins. MLH1 is unique among these proteins because it is also required for high levels of ...

Somatic Genome Variation

Somatic Genome Variation
  • Author : Xiu-Qing Li
  • Publisher : John Wiley & Sons
  • Release Date : 2017-06-26
  • Total pages : 448
  • ISBN : 0323856802
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Summary : Written by an international team of experts, Somatic Genome Variation presents a timely summary of the latest understanding of somatic genome development and variation in plants, animals, and microorganisms. Wide-ranging in coverage, the authors provide an updated view of somatic genomes and genetic theories while also offering interpretations of somatic ...

Genome Stability

Genome Stability
  • Author : James Haber
  • Publisher : Garland Pub
  • Release Date : 2014
  • Total pages : 399
  • ISBN : 0323856802
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Summary : "Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An ...

Maintaining Genome Stability The Role of Helicases and Deaminases

Maintaining Genome Stability  The Role of Helicases and Deaminases
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 90
  • ISBN : 0323856802
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Summary : Both helicases and deaminases are enzymes that play an important role in maintaining genomic stability and immune responses. Errors in duplicating DNA can result in genomic instability, leading to various human diseases, such as cancer, immune system disorder, muscle dystrophy, and neurodegenerations. Thus, maintaining genomic integrity is vital to the ...

DNA Damage Genome Stability and Human Disease

DNA Damage  Genome Stability and Human Disease
  • Author : Yuejin Hua,Hari S. Misra,Anthony Davis
  • Publisher : Frontiers Media SA
  • Release Date : 2022-01-27
  • Total pages : 212
  • ISBN : 0323856802
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Summary : Download or read online DNA Damage Genome Stability and Human Disease written by Yuejin Hua,Hari S. Misra,Anthony Davis, published by Frontiers Media SA which was released on 2022-01-27. Get DNA Damage Genome Stability and Human Disease Books now! Available in PDF, ePub and Kindle....

MicroRNA Signatures in Plant Genome Stability and Genotoxic Stress

MicroRNA Signatures in Plant Genome Stability and Genotoxic Stress
  • Author : Anca Macovei,Ignacio Rubio Somoza,Jorge Almiro P. Paiva,Susana Araújo,Mattia Donà
  • Publisher : Frontiers Media SA
  • Release Date : 2021-05-25
  • Total pages : 212
  • ISBN : 0323856802
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Summary : Download or read online MicroRNA Signatures in Plant Genome Stability and Genotoxic Stress written by Anca Macovei,Ignacio Rubio Somoza,Jorge Almiro P. Paiva,Susana Araújo,Mattia Donà, published by Frontiers Media SA which was released on 2021-05-25. Get MicroRNA Signatures in Plant Genome Stability and Genotoxic Stress ...

The Genome Stability is Preserved by a Stress Response Protein CCDC6

The Genome Stability is Preserved by a Stress Response Protein  CCDC6
  • Author : Chiara Luise,Angela Celetti
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2012-07
  • Total pages : 80
  • ISBN : 0323856802
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Summary : The maintenance of genomic stability is beneficial for the survival of an individual cell and crucial for cancer avoidance. Cells invest huge resources to maintain genomic stability, and cancer cells undergo an array of genetic changes to escape these barriers. The initiation of carcinogenesis represents a mutational event, which in ...

Human Papillomavirus Oncoproteins Alter Genomic Stability and Regulate the Viral Life Cycle

Human Papillomavirus Oncoproteins Alter Genomic Stability and Regulate the Viral Life Cycle
  • Author : Jennifer Teresa Thomas
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 141
  • ISBN : 0323856802
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Summary : Understanding how human papillomaviruses (HPVs) induce the proliferative lesions associated with genital warts and cervical cancers relies on our appreciation of the functions of the E6 and E7 viral proteins. These "oncoproteins" of the high risk HPV types interfere with the activities of cellular tumor suppressor proteins; E7 proteins act ...

Investigations Into Mitochondrial Genome Evolution Using Daphnia

Investigations Into Mitochondrial Genome Evolution Using Daphnia
  • Author : Susanne Paland
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 160
  • ISBN : 0323856802
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Summary : Download or read online Investigations Into Mitochondrial Genome Evolution Using Daphnia written by Susanne Paland, published by which was released on 2004. Get Investigations Into Mitochondrial Genome Evolution Using Daphnia Books now! Available in PDF, ePub and Kindle....