Epigenetics of Chronic Pain

Written By Anonim
Epigenetics of Chronic Pain
  • Publsiher : Academic Press
  • Release : 29 October 2018
  • ISBN : 0128140712
  • Pages : 248 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Epigenetics of Chronic Pain written by Anonim which was release on 29 October 2018, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined, with data derived from epigenetic studies on peripheral and central mechanisms of pain sensitivity in animal models and clinical cases studies. The studies and case examples cited highlight therapeutic pathways of significance and next steps for researchers to develop epigenetic-based treatments for chronic pain. In recent years, epigenetic regulation of gene expression has been shown to play a central role in managing human pain sensitivity. Findings show that expression of many genes critical to increases or decreases in pain sensitivity are indeed regulated by DNA methylation and its enzymes, histone-involved chromatin remodeling, and noncoding RNAs, mainly microRNAs. Compiles all known information on epigenetic regulation of chronic pain in one volume Covers the basic functionality of epigenetic mechanisms involved in pain management, applications of recent research in understanding different types of chronic pain, and pathways for developing therapeutics Leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss epigenetics in inflammatory, neuropathic, visceral, and other pain models in-depth Enables clinicians, researchers, and pharmacologists to better understand and treat chronic pain

Epigenetics of Chronic Pain

Epigenetics of Chronic Pain
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-10-29
  • Total pages : 248
  • ISBN : 0128140712
GET BOOK

Summary : Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, ...

Chronic Pain and DNA Methylation in the Mouse Prefrontal Cortex

Chronic Pain and DNA Methylation in the Mouse Prefrontal Cortex
  • Author : Lucas Topham
  • Publisher : Unknown
  • Release Date : 2021
  • Total pages : 212
  • ISBN : 0128140712
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Summary : "Chronic pain is one of the leading causes of disability and reduced quality of life worldwide. As a result of chronic pain, the prefrontal cortex (PFC) undergoes significant structural and functional remodeling, resulting in the loss of grey matter, altered synapse formation, and changes in neurotransmitter and ion channel signalling. ...

Chronic Pain New Insights for the Healthcare Professional 2013 Edition

Chronic Pain  New Insights for the Healthcare Professional  2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-07-22
  • Total pages : 193
  • ISBN : 0128140712
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Summary : Chronic Pain: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Chronic Pain: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional ...

Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release Date : 2016-12-30
  • Total pages : 324
  • ISBN : 0128140712
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Summary : Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as ...

Medical Epigenetics

Medical Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-08-27
  • Total pages : 970
  • ISBN : 0128140712
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Summary : Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human ...

Medical Epigenetics

Medical Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2016-06-21
  • Total pages : 924
  • ISBN : 0128140712
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Summary : Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of ...

Genomic Adaptation to Disease

Genomic Adaptation to Disease
  • Author : Sebastian Alvarado
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 212
  • ISBN : 0128140712
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Summary : "Cancer and chronic pain are two common pathologies affecting millions of patients worldwide. Much like most other disease states, they can be determined genetically, environmentally, or both. Unlike the static genome, the epigenome is responsible for interpreting environmental interactions and is often altered in disease states. A subset of epigenetic ...

Personalized Epigenetics

Personalized Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2015-04-28
  • Total pages : 610
  • ISBN : 0128140712
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Summary : Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and ...

Breaking the Fibro Code

Breaking the Fibro Code
  • Author : Penny D Chiasson
  • Publisher : Unknown
  • Release Date : 2022-03-31
  • Total pages : 124
  • ISBN : 0128140712
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Summary : You can design your destiny. The power is within you to conquer a life over shadowed by pain and hopelessness. Have you been told, like most other chronic pain sufferers that you must simply live with it? This is not true, and I am here to introduce you to tips ...

Translational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease
  • Author : Stephen Sonis,Alessandro Villa
  • Publisher : Academic Press
  • Release Date : 2019-09-14
  • Total pages : 458
  • ISBN : 0128140712
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Summary : Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral ...

The Epigenetics of Autoimmunity

The Epigenetics of Autoimmunity
  • Author : Rongxin Zhang
  • Publisher : Academic Press
  • Release Date : 2018-04-25
  • Total pages : 432
  • ISBN : 0128140712
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Summary : The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic ...

Epigenetics Methods

Epigenetics Methods
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2020-07-08
  • Total pages : 736
  • ISBN : 0128140712
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Summary : In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools ...

Epigenetics and Metabolomics

Epigenetics and Metabolomics
  • Author : Paban K. Agrawala,Poonam Rana
  • Publisher : Elsevier
  • Release Date : 2021-08-25
  • Total pages : 476
  • ISBN : 0128140712
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Summary : Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic ...

Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-05-18
  • Total pages : 518
  • ISBN : 0128140712
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Summary : Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ...

Epigenetics in Precision Medicine

Epigenetics in Precision Medicine
  • Author : Jose Luis Garcia-Gimenez
  • Publisher : Elsevier
  • Release Date : 2021-11-22
  • Total pages : 614
  • ISBN : 0128140712
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Summary : In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of ...