Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

Written By Adeboye Adejare
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders
  • Publsiher : Academic Press
  • Release : 20 September 2016
  • ISBN : 0128028114
  • Pages : 316 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders written by Adeboye Adejare which was release on 20 September 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders. Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders
  • Author : Adeboye Adejare
  • Publisher : Academic Press
  • Release Date : 2016-09-20
  • Total pages : 316
  • ISBN : 0128028114
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Summary : Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and ...

Drug Repositioning

Drug Repositioning
  • Author : Joel Dudley,Laura Berliocchi
  • Publisher : CRC Press
  • Release Date : 2017-07-14
  • Total pages : 313
  • ISBN : 0128028114
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Summary : Nervous system diseases represent a major health concern worldwide. Although important financial and professional investment, their etiology and pathophysiology still remain mostly elusive. Moreover, the clinical need of disease-modifying therapies is still unmet. In the last decades, traditional R&D has failed in identifying new effective therapies in many medical ...

Principles of Neurochemistry

Principles of Neurochemistry
  • Author : Bijo Mathew,Della Grace Thomas Parambi
  • Publisher : Springer Nature
  • Release Date : 2020-09-21
  • Total pages : 194
  • ISBN : 0128028114
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Summary : This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines. As drug discovery for neurodegenerative diseases is one of the largest subspecialties in the field of medicine, the ...

Frontiers in Clinical Drug Research CNS and Neurological Disorders

Frontiers in Clinical Drug Research   CNS and Neurological Disorders
  • Author : Atta-ur- Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2017-12-21
  • Total pages : 290
  • ISBN : 0128028114
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Summary : Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range ...

Therapies for Retinal Degeneration

Therapies for Retinal Degeneration
  • Author : Enrique J. de la Rosa,Thomas G. Cotter
  • Publisher : Royal Society of Chemistry
  • Release Date : 2018-09-18
  • Total pages : 260
  • ISBN : 0128028114
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Summary : Sight loss and blindness is a very prevalent cause of disability. Retinal diseases leading to visual loss affect many people worldwide and the search for adequate drugs remains a challenge and an important area of interest in the drug discovery field. This book addresses approaches to the treatment of retinal ...

Functional Foods and Therapeutic Strategies for Neurodegenerative Disorders

Functional Foods and Therapeutic Strategies for Neurodegenerative Disorders
  • Author : Preetham Elumalai,Sreeja Lakshmi
  • Publisher : Springer Nature
  • Release Date : 2022
  • Total pages : 227
  • ISBN : 0128028114
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Summary : This book provides a comprehensive summary of the latest knowledge regarding functional foods and new therapeutic strategies for neurodegenerative disorders through explaining specific mechanisms for natural remedies and functional foods as well as alternative treatment and supplementary approaches for neurodegenerative diseases. Many relevant topics are covered, including role of prebiotics, ...

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-03
  • Total pages : 731
  • ISBN : 0128028114
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Summary : The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/...

Nanomedical Drug Delivery for Neurodegenerative Diseases

Nanomedical Drug Delivery for Neurodegenerative Diseases
  • Author : Awesh K. Yadav,Rahul Shukla,S.J.S. Flora
  • Publisher : Academic Press
  • Release Date : 2022-03-10
  • Total pages : 282
  • ISBN : 0128028114
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Summary : Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, ...

Drug Design and Discovery in Alzheimer s Disease

Drug Design and Discovery in Alzheimer   s Disease
  • Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary
  • Publisher : Elsevier
  • Release Date : 2015-06-27
  • Total pages : 784
  • ISBN : 0128028114
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Summary : Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, ...

Remington

Remington
  • Author : Adeboye Adejare
  • Publisher : Academic Press
  • Release Date : 2020-11-03
  • Total pages : 1030
  • ISBN : 0128028114
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Summary : Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the ...

Frontiers in Clinical Drug Research CNS and Neurological Disorders Volume 10

Frontiers in Clinical Drug Research   CNS and Neurological Disorders  Volume 10
  • Author : Atta-ur-Rahman,Zareen Amtul
  • Publisher : Bentham Science Publishers
  • Release Date : 2022-04-07
  • Total pages : 360
  • ISBN : 0128028114
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Summary : Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range ...

The Pharmacology of Neurogenesis and Neuroenhancement

The Pharmacology of Neurogenesis and Neuroenhancement
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2007-01-16
  • Total pages : 344
  • ISBN : 0128028114
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Summary : Currently, few drugs are available for the effective treatment of neurodegenerative diseases and neurodevelopmental disorders. Recent advances in neuroscience research offer hope that future strategies for treating these brain disorders will include neurogenesis and neuroenhancement as therapeutic endpoints. This volume reviews cutting-edge findings related to the pharmacological aspects of neurogenesis ...

Neurobiology of Huntington s Disease

Neurobiology of Huntington   s Disease
  • Author : Donald C. Lo,Robert E. Hughes
  • Publisher : CRC Press
  • Release Date : 2010-07-02
  • Total pages : 338
  • ISBN : 0128028114
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Summary : In 1993, the genetic mutation responsible for Huntington’s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations ...

Frontiers in Clinical Drug Research Dementia Volume 1

Frontiers in Clinical Drug Research   Dementia  Volume 1
  • Author : Atta-ur-Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2020-06-02
  • Total pages : 261
  • ISBN : 0128028114
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Summary : Frontiers in Clinical Drug Research - Dementia is a book series which presents comprehensive reviews about research on Dementia, - the loss of brain function associated with Alzheimer’s disease and other related medical conditions. The disease affects the parts of the brain that deal with memory, thought, and language. ...

Neurodegenerative Diseases Integrative PPPM Approach as the Medicine of the Future

Neurodegenerative Diseases  Integrative PPPM Approach as the Medicine of the Future
  • Author : Silvia Mandel
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-12
  • Total pages : 398
  • ISBN : 0128028114
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Summary : This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects ...