Advances in DNA Repair in Cancer Therapy

Written By Lawrence Panasci
Advances in DNA Repair in Cancer Therapy
  • Publsiher : Springer Science & Business Media
  • Release : 09 December 2012
  • ISBN : 1461447410
  • Pages : 312 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Advances in DNA Repair in Cancer Therapy written by Lawrence Panasci which was release on 09 December 2012, this book published by Springer Science & Business Media. Available in PDF, EPUB and Kindle Format. Book excerpt: ​A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.​

DNA Repair in Cancer Therapy

DNA Repair in Cancer Therapy
  • Author : Mark R. Kelley,Melissa L. Fishel
  • Publisher : Academic Press
  • Release Date : 2016-06-07
  • Total pages : 464
  • ISBN : 1461447410
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Summary : DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. Experts on DNA repair proteins ...

Advances in DNA Repair in Cancer Therapy

Advances in DNA Repair in Cancer Therapy
  • Author : Lawrence Panasci,Raquel Aloyz,Moulay Alaoui-Jamali
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-09
  • Total pages : 312
  • ISBN : 1461447410
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Summary : ​A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of ...

DNA Repair in Cancer Therapy

DNA Repair in Cancer Therapy
  • Author : Lawrence C. Panasci,Moulay A. Alaoui-Jamali
  • Publisher : Springer Science & Business Media
  • Release Date : 2004-03-19
  • Total pages : 363
  • ISBN : 1461447410
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Summary : A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors ...

DNA Repair and Cancer

DNA Repair and Cancer
  • Author : Srinivasan Madhusudan,David M. Wilson III
  • Publisher : CRC Press
  • Release Date : 2013-01-22
  • Total pages : 718
  • ISBN : 1461447410
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Summary : DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics ...

The Role of DNA Repair Pathways in Resistance to Chemotherapy and Radiotherapy in Cancer

The Role of DNA Repair Pathways in Resistance to Chemotherapy and Radiotherapy in Cancer
  • Author : José Díaz-Chávez,Rosa Maria Bermudez-Cruz,David Y. Lee
  • Publisher : Frontiers Media SA
  • Release Date : 2022-04-29
  • Total pages : 212
  • ISBN : 1461447410
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Summary : Download or read online The Role of DNA Repair Pathways in Resistance to Chemotherapy and Radiotherapy in Cancer written by José Díaz-Chávez,Rosa Maria Bermudez-Cruz,David Y. Lee, published by Frontiers Media SA which was released on 2022-04-29. Get The Role of DNA Repair Pathways in Resistance ...

Targeting the DNA Damage Response for Anti Cancer Therapy

Targeting the DNA Damage Response for Anti Cancer Therapy
  • Author : John Pollard,Nicola Curtin
  • Publisher : Springer
  • Release Date : 2018-05-26
  • Total pages : 401
  • ISBN : 1461447410
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Summary : Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care across multiple cancer types. It ...

DNA Repair and Resistance to Cancer Therapy

DNA Repair and Resistance to Cancer Therapy
  • Author : António S. Rodrigues
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 212
  • ISBN : 1461447410
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Summary : DNA Repair and Resistance to Cancer Therapy....

PARP Inhibitors for Cancer Therapy

PARP Inhibitors for Cancer Therapy
  • Author : Nicola J. Curtin,Ricky A. Sharma
  • Publisher : Humana Press
  • Release Date : 2015-06-13
  • Total pages : 591
  • ISBN : 1461447410
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Summary : PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA ...

DNA Repair Cancer and Cancer Therapy

DNA Repair  Cancer and Cancer Therapy
  • Author : Mu Wang
  • Publisher : Unknown
  • Release Date : 2011
  • Total pages : 212
  • ISBN : 1461447410
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Summary : Download or read online DNA Repair Cancer and Cancer Therapy written by Mu Wang, published by which was released on 2011. Get DNA Repair Cancer and Cancer Therapy Books now! Available in PDF, ePub and Kindle....

System Biology Analysis of the Role of DNA Repair in Cancer Treatment Outcome

System Biology Analysis of the Role of DNA Repair in Cancer Treatment Outcome
  • Author : Mengdi Qian
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 212
  • ISBN : 1461447410
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Summary : Cancer is one of the most lethal and hard to cure diseases. The common treatments for cancer include surgery, radiation therapy, chemotherapy, immunotherapy and hormone therapy. Ionizing radiation (IR) is one of the main clinical treatments for cancer and it works by inducing DNA double strand breaks (DSBs), which are ...

Cancer Therapeutics Targeting DNA Repair Pathways

Cancer Therapeutics  Targeting DNA Repair Pathways
  • Author : Amila Suraweera,James A. L. Brown,Martin Francis Lavin,Yi Chieh Lim
  • Publisher : Frontiers Media SA
  • Release Date : 2022-03-10
  • Total pages : 212
  • ISBN : 1461447410
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Summary : Download or read online Cancer Therapeutics Targeting DNA Repair Pathways written by Amila Suraweera,James A. L. Brown,Martin Francis Lavin,Yi Chieh Lim, published by Frontiers Media SA which was released on 2022-03-10. Get Cancer Therapeutics Targeting DNA Repair Pathways Books now! Available in PDF, ePub and Kindle....

DNA Repair Genetic Instability and Cancer

DNA Repair  Genetic Instability  and Cancer
  • Author : Qingyi Wei,Dr. Lei Li,Dr. David Chen
  • Publisher : World Scientific
  • Release Date : 2007
  • Total pages : 353
  • ISBN : 1461447410
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Summary : This volume describes the elaborate surveillance systems and various DNA repair mechanisms that ensure accurate passage of genetic information onto daughter cells. In particular, it narrates how the cell cycle checkpoint and DNA repair machineries detect and restore DNA damages that are embedded in millions to billions of normal base ...

Cancer Associated Defects in the DNA Damage Response Drivers for Malignant Transformation and Potential Therapeutic Targets

Cancer Associated Defects in the DNA Damage Response  Drivers for Malignant Transformation and Potential Therapeutic Targets
  • Author : Marcel van Vugt,H. Christian Reinhardt
  • Publisher : Frontiers Media SA
  • Release Date : 2016-10-17
  • Total pages : 111
  • ISBN : 1461447410
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Summary : For this eBook, and the associated Research Topic in Frontiers in Genetics, entitled: ‘Cancer-associated defects in the DNA damage response: drivers for malignant transformation and potential therapeutic targets’ we have selected 10 papers that each discusses important, yet distinct aspects of the response to DNA damage in normal cells and cancer ...

Inhibition of RAD52 based DNA Repair for Cancer Therapy

Inhibition of RAD52 based DNA Repair for Cancer Therapy
  • Author : Mona Hadi Al-Mugotir
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 172
  • ISBN : 1461447410
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Summary : Germline BRCA mutations underlay a significant risk for breast and ovarian cancer that increases in age. BRCA mutations are usually associated with the most aggressive subtypes of these cancers such as triple negative breast cancer and high-grade serous ovarian cancer. Conventional chemotherapeutic or hormonal therapies do not address the molecular ...

DNA Damage Repair and Misrepair in Cancer and in Cancer Therapy

DNA Damage  Repair and Misrepair in Cancer and in Cancer Therapy
  • Author : Ana M. Urbano,Carlos F. Rodrigues,Joana F. Cerveira,Leonardo M. R. Ferreira,Maria C. Alpoim
  • Publisher : Unknown
  • Release Date : 2011
  • Total pages : 212
  • ISBN : 1461447410
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Summary : Download or read online DNA Damage Repair and Misrepair in Cancer and in Cancer Therapy written by Ana M. Urbano,Carlos F. Rodrigues,Joana F. Cerveira,Leonardo M. R. Ferreira,Maria C. Alpoim, published by which was released on 2011. Get DNA Damage Repair and Misrepair in Cancer and in Cancer ...