Bioreactor Modeling

Written By Jerome Morchain
Bioreactor Modeling
  • Publsiher : Elsevier
  • Release : 06 October 2017
  • ISBN : 0081011660
  • Pages : 218 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Bioreactor Modeling written by Jerome Morchain which was release on 06 October 2017, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand, have the ability to modulate the rate of substrate assimilation. Moreover, the nature of the biochemical transformations results from a compromise between the needs of the cell and the available resources. This book revisits the modeling of bioreactors using a multi-scale approach. It addresses issues related to mixing, phase-to-phase transfers and the adaptation of microorganisms to variations in concentration, and explores the use of population balances for the simulation of bioreactors. By adopting a multidisciplinary perspective that draws on process engineering, fluid mechanics and microbiology, this book sheds new light on the particularity of bioprocesses in relation to physical and chemical phenomena. Presents a multiphase description of bioreactor modeling Includes a combination of concepts issued from different scientific fields to address a practical issue Provides a detailed description of the population balance concept as applied to biological systems Covers a set of illustrative examples of the interaction between hydrodynamics and biological response

Bioreactor Modeling

Bioreactor Modeling
  • Author : Jerome Morchain
  • Publisher : Elsevier
  • Release Date : 2017-10-06
  • Total pages : 218
  • ISBN : 0081011660
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Summary : Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In ...

Solid State Fermentation Bioreactors

Solid State Fermentation Bioreactors
  • Author : David A. Mitchell,Nadia Krieger,Marin Berovic
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-08-02
  • Total pages : 448
  • ISBN : 0081011660
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Summary : This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. The authors survey bioreactor types in common use, and describe in depth how to plan a project, and model heat transfer ...

Computational Modeling in Biomechanics

Computational Modeling in Biomechanics
  • Author : Suvranu De,Farshid Guilak,Mohammad Mofrad
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-03-10
  • Total pages : 581
  • ISBN : 0081011660
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Summary : Availability of advanced computational technology has fundamentally altered the investigative paradigm in the field of biomechanics. Armed with sophisticated computational tools, researchers are seeking answers to fundamental questions by exploring complex biomechanical phenomena at the molecular, cellular, tissue and organ levels. The computational armamentarium includes such diverse tools as the ...

Bioreactors

Bioreactors
  • Author : Carl-Fredrik Mandenius
  • Publisher : John Wiley & Sons
  • Release Date : 2016-02-16
  • Total pages : 520
  • ISBN : 0081011660
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Summary : In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and ...

An Introduction to Bioreactor Hydrodynamics and Gas Liquid Mass Transfer

An Introduction to Bioreactor Hydrodynamics and Gas Liquid Mass Transfer
  • Author : Enes Kadic,Theodore J. Heindel
  • Publisher : John Wiley & Sons
  • Release Date : 2014-03-14
  • Total pages : 328
  • ISBN : 0081011660
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Summary : Reviews and compares the major types of bioreactors, defines their pros and cons, and identifies research needs and figures of merit that have yet to be addressed Describes common modes of operation in bioreactors Covers the three common bioreactor types, including stirred-tank bioreactors, bubble column bioreactors, and airlift bioreactors Details ...

Computational Modeling in Bioengineering and Bioinformatics

Computational Modeling in Bioengineering and Bioinformatics
  • Author : Nenad Filipovic
  • Publisher : Academic Press
  • Release Date : 2019-10-09
  • Total pages : 442
  • ISBN : 0081011660
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Summary : Computational Modeling in Bioengineering and Bioinformatics promotes complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, and in the environment, public health, drug design, and so on. It provides a common platform by bridging these two very important and complementary ...

Bioreactor System Design

Bioreactor System Design
  • Author : Juan A. Asenjo
  • Publisher : CRC Press
  • Release Date : 1994-11-17
  • Total pages : 648
  • ISBN : 0081011660
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Summary : Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such as ...

Bioreactors

Bioreactors
  • Author : Goutam Saha,Alok Barua,Satyabroto Sinha
  • Publisher : CRC Press
  • Release Date : 2017-12-01
  • Total pages : 136
  • ISBN : 0081011660
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Summary : Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its ...

Biological Reaction Engineering

Biological Reaction Engineering
  • Author : Elmar Heinzle,Irving J. Dunn,John Ingham,Jiří E. Přenosil
  • Publisher : John Wiley & Sons
  • Release Date : 2021-04-26
  • Total pages : 560
  • ISBN : 0081011660
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Summary : This practical book presents the modeling of dynamic biological engineering processes in a readily comprehensible manner, using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples illustrate almost every aspect of biological engineering science, with each ...

Hybrid Modeling in Process Industries

Hybrid Modeling in Process Industries
  • Author : Jarka Glassey,Moritz von Stosch
  • Publisher : CRC Press
  • Release Date : 2018-03-08
  • Total pages : 219
  • ISBN : 0081011660
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Summary : This title introduces the underlying theory and demonstrates practical applications in different process industries using hybrid modeling. The fundamental part covers questions on “How to develop a hybrid model?”, “How to represent and identify unknown parts?”, “How to enhance the model quality by design of experiments?” and “How to compare ...

Methods in Computational Biology

Methods in Computational Biology
  • Author : Ross Carlson,Herbert Sauro
  • Publisher : MDPI
  • Release Date : 2019-07-03
  • Total pages : 214
  • ISBN : 0081011660
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Summary : Modern biology is rapidly becoming a study of large sets of data. Understanding these data sets is a major challenge for most life sciences, including the medical, environmental, and bioprocess fields. Computational biology approaches are essential for leveraging this ongoing revolution in omics data. A primary goal of this Special ...

Techno economics and Life Cycle Assessment of Bioreactors

Techno economics and Life Cycle Assessment of Bioreactors
  • Author : Puranjan Mishra,Lakhveer Singh,Pooja Ghosh
  • Publisher : Elsevier
  • Release Date : 2022-06-24
  • Total pages : 246
  • ISBN : 0081011660
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Summary : Techno-economics and Life Cycle Assessment of Bioreactors: Post-Covid19 Waste Management Approach covers the emerging trends in bioreactor research, including techno-economics and life cycle assessment perspectives, both key considerations in making the anaerobic-digestion process technically feasible, economically viable and environmentally sustainable. The book is divided into three sections, with an introductory ...

The Control Handbook three volume set

The Control Handbook  three volume set
  • Author : William S. Levine
  • Publisher : CRC Press
  • Release Date : 2018-10-08
  • Total pages : 3526
  • ISBN : 0081011660
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Summary : At publication, The Control Handbook immediately became the definitive resource that engineers working with modern control systems required. Among its many accolades, that first edition was cited by the AAP as the Best Engineering Handbook of 1996. Now, 15 years later, William Levine has once again compiled the most comprehensive and authoritative ...

Industrial Microbiology

Industrial Microbiology
  • Author : David B. Wilson,Hermann Sahm,Klaus-Peter Stahmann,Mattheos Koffas
  • Publisher : John Wiley & Sons
  • Release Date : 2019-11-21
  • Total pages : 424
  • ISBN : 0081011660
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Summary : Focusing on current and future uses of microbes as production organisms, this practice-oriented textbook complements traditional texts on microbiology and biotechnology. The editors have brought together leading researchers and professionals from the entire field of industrial microbiology and together they adopt a modern approach to a well-known subject. Following a ...

The Prospect of Industry 5 0 in Biomanufacturing

The Prospect of Industry 5 0 in Biomanufacturing
  • Author : Pau Loke Show,Kit Wayne Chew,Tau Chuan Ling
  • Publisher : CRC Press
  • Release Date : 2021-07-02
  • Total pages : 326
  • ISBN : 0081011660
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Summary : This is the first book to present the idea of Industry 5.0 in biomanufacturing and bioprocess engineering, both upstream and downstream. The Prospect of Industry 5.0 in Biomanufacturing details the latest technologies and how they can be used efficiently and explains process analysis from an engineering point of view. In addition, it ...