Big Mechanisms in Systems Biology

Written By Bor-Sen Chen
Big Mechanisms in Systems Biology
  • Publsiher : Academic Press
  • Release : 25 October 2016
  • ISBN : 0128097078
  • Pages : 878 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Big Mechanisms in Systems Biology written by Bor-Sen Chen which was release on 25 October 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research. Written in a didactic manner in order to explain how to investigate Big Mechanisms by big data mining and system identification Provides more than 140 diagrams to illustrate Big Mechanism in systems biology Presents worked examples in each chapter

Big Mechanisms in Systems Biology

Big Mechanisms in Systems Biology
  • Author : Bor-Sen Chen,Cheng-Wei Li
  • Publisher : Academic Press
  • Release Date : 2016-10-25
  • Total pages : 878
  • ISBN : 0128097078
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Summary : Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with ...

Systems Cancer Biology

Systems Cancer Biology
  • Author : Bor-Sen Chen
  • Publisher : Cambridge Scholars Publishing
  • Release Date : 2021-07-13
  • Total pages : 632
  • ISBN : 0128097078
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Summary : Cancer is a complex and heterogeneous (systematic) disease that exhibits high levels of robustness against various therapeutic interventions. Due to the complex, heterogeneous, and evolving nature of cancer, it is essential for a system-oriented view to be adopted in order to understand the pathogenic mechanism of cancer which will eventually ...

Investigation of Genetic and Epigenetic Networks for Differential Cellular Mechanisms Between Normal Developing and Regenerating Livers Via Systems Biology Method and Big Data Mining

Investigation of Genetic and Epigenetic Networks for Differential Cellular Mechanisms Between Normal  Developing and Regenerating Livers Via Systems Biology Method and Big Data Mining
  • Author : Shang-Wen Wong
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 0128097078
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Summary : Download or read online Investigation of Genetic and Epigenetic Networks for Differential Cellular Mechanisms Between Normal Developing and Regenerating Livers Via Systems Biology Method and Big Data Mining written by Shang-Wen Wong, published by which was released on 2017. Get Investigation of Genetic and Epigenetic Networks for Differential Cellular Mechanisms Between ...

Systems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology
  • Author : Bor-Sen Chen
  • Publisher : Academic Press
  • Release Date : 2021-03-16
  • Total pages : 672
  • ISBN : 0128097078
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Summary : Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate development procedures and help users understand the results of systems immunology and infection microbiology. Chapters discuss systems immunology, systems infection microbiology, systematic inflammation and immune responses in restoration and regeneration process, systems' ...

Systems Biology and the Challenge of Deciphering the Metabolic Mechanisms Underlying Cancer

Systems Biology and the Challenge of Deciphering the Metabolic Mechanisms Underlying Cancer
  • Author : Osbaldo Resendis-Antonio,Christian Diener
  • Publisher : Frontiers Media SA
  • Release Date : 2017-11-23
  • Total pages : 212
  • ISBN : 0128097078
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Summary : Since the discovery of the Warburg effect in the 1920s cancer has been tightly associated with the genetic and metabolic state of the cell. One of the hallmarks of cancer is the alteration of the cellular metabolism in order to promote proliferation and undermine cellular defense mechanisms such as apoptosis ...

Systems Biology

Systems Biology
  • Author : Dimitrios Vlachakis
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-06-19
  • Total pages : 106
  • ISBN : 0128097078
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Summary : Systems biology is the inevitable outcome of long years of knowledge acquisition and data accumulation. The aim of systems biology is to integrate in a seamless way all existing knowledge in interconnected disciplines, stretching from modern biomedical research to physics, chemistry, and mathematics. The main integration tool of such complex ...

Computational Methods in Systems Biology

Computational Methods in Systems Biology
  • Author : Jérôme Feret,Heinz Koeppl
  • Publisher : Springer
  • Release Date : 2017-09-18
  • Total pages : 332
  • ISBN : 0128097078
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Summary : This book constitutes the refereed proceedings of the 15th International Conference on Computational Methods in Systems Biology, CMSB 2017, held in Darmstadt, Germany, in September 2017. The 15 full papers, 4 tool papers and 4 posters presented together with 1 invited talk were carefully reviewed and selected from 41 regular paper submissions. Topics of interest include formalisms ...

Bioinformatics in the Era of Post Genomics and Big Data

Bioinformatics in the Era of Post Genomics and Big Data
  • Author : Ibrokhim Y. Abdurakhmonov
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-06-20
  • Total pages : 188
  • ISBN : 0128097078
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Summary : Bioinformatics has evolved significantly in the era of post genomics and big data. Huge advancements were made toward storing, handling, mining, comparing, extracting, clustering and analysis as well as visualization of big macromolecular data using novel computational approaches, machine and deep learning methods, and web-based server tools. There are extensively ...

Systems Biology

Systems Biology
  • Author : Lilia Alberghina,Hans V. Westerhoff
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-10-04
  • Total pages : 408
  • ISBN : 0128097078
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Summary : For life to be understood and disease to become manageable, the wealth of postgenomic data now needs to be made dynamic. This development requires systems biology, integrating computational models for cells and organisms in health and disease; quantitative experiments (high-throughput, genome-wide, living cell, in silico); and new concepts and principles ...

Data Driven Innovation Big Data for Growth and Well Being

Data Driven Innovation Big Data for Growth and Well Being
  • Author : OECD
  • Publisher : OECD Publishing
  • Release Date : 2015-10-06
  • Total pages : 456
  • ISBN : 0128097078
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Summary : This report improves the evidence base on the role of Data Driven Innovation for promoting growth and well-being, and provide policy guidance on how to maximise the benefits of DDI and mitigate the associated economic and societal risks....

Computational Systems Biology

Computational Systems Biology
  • Author : Helder I Nakaya
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-26
  • Total pages : 548
  • ISBN : 0128097078
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Summary : Download or read online Computational Systems Biology written by Helder I Nakaya, published by Elsevier Inc. Chapters which was released on 2013-11-26. Get Computational Systems Biology Books now! Available in PDF, ePub and Kindle....

Computational Methods in Systems Biology

Computational Methods in Systems Biology
  • Author : Milan Češka,David Šafránek
  • Publisher : Springer
  • Release Date : 2018-08-27
  • Total pages : 326
  • ISBN : 0128097078
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Summary : This book constitutes the refereed proceedings of the 16th International Conference on Computational Methods in Systems Biology, CMSB 2018, held in BRNO, Czech Republic, in September 2018. The 15 full and 7 short papers presented together with 5 invited talks were carefully reviewed and selected from 46 submissions. Topics of interest include formalisms for modeling biological ...

Applying Big Data Analytics in Bioinformatics and Medicine

Applying Big Data Analytics in Bioinformatics and Medicine
  • Author : Lytras, Miltiadis D.,Papadopoulou, Paraskevi
  • Publisher : IGI Global
  • Release Date : 2017-06-16
  • Total pages : 465
  • ISBN : 0128097078
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Summary : Many aspects of modern life have become personalized, yet healthcare practices have been lagging behind in this trend. It is now becoming more common to use big data analysis to improve current healthcare and medicinal systems, and offer better health services to all citizens. Applying Big Data Analytics in Bioinformatics ...

Big Data Analytics in Bioinformatics and Healthcare

Big Data Analytics in Bioinformatics and Healthcare
  • Author : Wang, Baoying
  • Publisher : IGI Global
  • Release Date : 2014-10-31
  • Total pages : 528
  • ISBN : 0128097078
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Summary : As technology evolves and electronic data becomes more complex, digital medical record management and analysis becomes a challenge. In order to discover patterns and make relevant predictions based on large data sets, researchers and medical professionals must find new methods to analyze and extract relevant health information. Big Data Analytics ...

Plant Single Cell Type Systems Biology

Plant Single Cell Type Systems Biology
  • Author : Marc Libault,Sixue Chen
  • Publisher : Frontiers Media SA
  • Release Date : 2016-09-06
  • Total pages : 212
  • ISBN : 0128097078
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Summary : The phenotype of a plant in response to a stress condition is the reflection of the molecular responses in different cell-types composing the plant. The multicellular complexity represents a challenge when accessing specific responses of each cell or cell type composing the plant. To overcome this difficulty and allow the ...