Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Written By Surendra Nimesh
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids
  • Publsiher : Woodhead Publishing
  • Release : 04 April 2017
  • ISBN : 0081005636
  • Pages : 256 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKAdvances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids


Read or download book entitled Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids written by Surendra Nimesh which was release on 04 April 2017, this book published by Woodhead Publishing. Available in PDF, EPUB and Kindle Format. Book excerpt: Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids
  • Author : Surendra Nimesh,Ramesh Chandra,Nidhi Gupta
  • Publisher : Woodhead Publishing
  • Release Date : 2017-04-04
  • Total pages : 256
  • ISBN : 0081005636
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Summary : Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive ...

Nanomedicine for Drug Delivery and Therapeutics

Nanomedicine for Drug Delivery and Therapeutics
  • Author : Ajay Kumar Mishra
  • Publisher : John Wiley & Sons
  • Release Date : 2013-02-01
  • Total pages : 536
  • ISBN : 0081005636
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Summary : This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses....

Nucleic Acids Chemistry

Nucleic Acids Chemistry
  • Author : Ramon Eritja
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release Date : 2021-01-18
  • Total pages : 380
  • ISBN : 0081005636
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Summary : This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as ...

Mixed Polymeric Micelles for Osteosarcoma Therapy Development and Characterization

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  • Publisher : Bentham Science Publishers
  • Release Date : 2022-03-09
  • Total pages : 120
  • ISBN : 0081005636
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Summary : Osteosarcoma is a rare bone tumor that has a high incidence amongchildren and young adults. Despite recent therapeutic developments, osteosarcomastill presents major hurdles to achieving successful results, mainly due to thepresence of multi-drug-resistant cells.This monograph primarily aims to provide information about the basicscience behind the treatment of osteosarcoma along ...

Nanotechnology in Biology and Medicine

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  • Author : Pradipta Ranjan Rauta,Yugal Kishore Mohanta,Debasis Nayak
  • Publisher : CRC Press
  • Release Date : 2019-10-10
  • Total pages : 273
  • ISBN : 0081005636
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Summary : Nanotechnology in biology and medicine: Research advancements & future perspectives is focused to provide an interdisciplinary, integrative overview on the developments made in nanotechnology till date along with the ongoing trends and the future prospects. It presents the basics, fundamental results/current applications and latest achievements on nanobiotechnological researches worldwide scientific ...

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  • Author : Sanyog Jain,Kaisar Raza,Ashish Kumar Agrawal,Ankur Vaidya
  • Publisher : Elsevier
  • Release Date : 2020-09-30
  • Total pages : 702
  • ISBN : 0081005636
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Summary : Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses ...

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  • Publisher : Academic Press
  • Release Date : 2021-07-28
  • Total pages : 324
  • ISBN : 0081005636
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Summary : Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living ...

Biomedical Applications of Nanotechnology

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  • Author : Vinod Labhasetwar,Diandra L. Leslie-Pelecky
  • Publisher : John Wiley & Sons
  • Release Date : 2007-09-28
  • Total pages : 272
  • ISBN : 0081005636
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Summary : An overview of nanotechnology and its potential The field of nanotechnology is undergoing rapid developments on many fronts. This reference provides a comprehensive review of various nanotechnologies with a view to their biomedical applications. With chapters contributed by distinguished scientists from diverse disciplines, Biomedical Applications of Nanotechnology : Reviews recent advances ...

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  • Author : Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
  • Publisher : CRC Press
  • Release Date : 2021-11-30
  • Total pages : 790
  • ISBN : 0081005636
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Summary : Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and ...

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  • Author : Ravin Narain
  • Publisher : Elsevier
  • Release Date : 2020-06-16
  • Total pages : 488
  • ISBN : 0081005636
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Summary : Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest ...

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  • Author : Alberto Signore,Luca Maria Sconfienza
  • Publisher : MDPI
  • Release Date : 2020-12-07
  • Total pages : 184
  • ISBN : 0081005636
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Summary : This Special Issue is a collection of selected papers from the 3rd European Congress on Imaging Infection and Inflammation (www.nuclearmedicinediscovery.org/events.asp) and results of consensus sessions by major experts in the field including Nuclear Medicine physicians, Radiologists, Clinicians and microbiologists. The Journal of Clinical Medicine (JCM) provides ...

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  • Author : Jayvadan K. Patel
  • Publisher : Springer Nature
  • Release Date : 2022-08-10
  • Total pages : 212
  • ISBN : 0081005636
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Summary : Download or read online Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems written by Jayvadan K. Patel, published by Springer Nature which was released on . Get Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems Books now! Available in PDF, ePub and Kindle....

Nanoalloys

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  • Author : Florent Calvo
  • Publisher : Elsevier
  • Release Date : 2020-06-26
  • Total pages : 524
  • ISBN : 0081005636
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Summary : Nanoalloys, Second Edition, provides a self-contained reference on the physics and chemistry of nanoscale alloys, dealing with all important aspects that range from the theoretical concepts and the practical synthesis methods to the characterization tools. The book also covers modern applications of nanoalloys in materials science, catalysis or nanomedicine and ...

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  • Author : Ajay Kumar,Amit Kishore Singh,Krishna Kumar Choudhary
  • Publisher : Woodhead Publishing
  • Release Date : 2019-06-20
  • Total pages : 352
  • ISBN : 0081005636
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Summary : Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology explores PGPMs (actinomycetes, bacteria, fungi and cyanobacteria) and their multidimensional roles in agriculture, including their increasing applications in sustainable agriculture. In addition to their traditional understanding and applications in agriculture, PGPMs are increasingly known as a source of nano-particles ...

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  • Author : Bhaskar Singh,Ramesh Oraon
  • Publisher : CRC Press
  • Release Date : 2022-09-22
  • Total pages : 310
  • ISBN : 0081005636
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Summary : Advanced Nanocatalysts for Biodiesel Production is a comprehensive and advanced book on practical and theoretical concepts of nanocatalysts dealing with future processing techniques towards environmental sustainability. The book critically discusses on latest emerging advanced nanocatalysts for biodiesel production aimed at reducing complexities and cost in the quest to meet future ...