Adenoviral Vectors for Gene Therapy

Written By David T. Curiel
Adenoviral Vectors for Gene Therapy
  • Publsiher : Academic Press
  • Release : 10 March 2016
  • ISBN : 0128005106
  • Pages : 868 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Adenoviral Vectors for Gene Therapy written by David T. Curiel which was release on 10 March 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
  • Author : David T. Curiel
  • Publisher : Academic Press
  • Release Date : 2016-03-10
  • Total pages : 868
  • ISBN : 0128005106
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Summary : Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing ...

Viral Vectors for Gene Therapy

Viral Vectors for Gene Therapy
  • Author : Curtis A. Machida
  • Publisher : Springer Science & Business Media
  • Release Date : 2003
  • Total pages : 608
  • ISBN : 0128005106
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Summary : Comprehensive and highly practical, Viral Vectors for Gene Therapy provides researchers with the basic tools needed to design targeted gene delivery vectors, and clinicians with an understanding of how to apply viral vectors to the treatment of genetic disorders. Offering detailed step-by-step instructions to ensure successful results, these experts detail ...

Adenoviral Vectors for Gene Therapy an Evaluation of New Methods and Strategies

Adenoviral Vectors for Gene Therapy  an Evaluation of New Methods and Strategies
  • Author : Frederik Hubertus Emanuel Schagen
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 152
  • ISBN : 0128005106
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Summary : Download or read online Adenoviral Vectors for Gene Therapy an Evaluation of New Methods and Strategies written by Frederik Hubertus Emanuel Schagen, published by which was released on 2002. Get Adenoviral Vectors for Gene Therapy an Evaluation of New Methods and Strategies Books now! Available in PDF, ePub and Kindle....

Therapeutic Applications of Adenoviruses

Therapeutic Applications of Adenoviruses
  • Author : Philip Ng,Nicola Brunetti-Pierri
  • Publisher : CRC Press
  • Release Date : 2016-12-12
  • Total pages : 256
  • ISBN : 0128005106
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Summary : Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy ...

A Guide to Human Gene Therapy

A Guide to Human Gene Therapy
  • Author : Roland W. Herzog,Sergei Zolotukhin
  • Publisher : World Scientific
  • Release Date : 2010
  • Total pages : 388
  • ISBN : 0128005106
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Summary : Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ( vector) to deliver ...

Nonviral Vectors for Gene Therapy

Nonviral Vectors for Gene Therapy
  • Author : Mien-Chie Hung,Leaf Huang,Ernst Wagner
  • Publisher : Elsevier
  • Release Date : 1999-07-01
  • Total pages : 456
  • ISBN : 0128005106
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Summary : Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of "healthy genes" into patients' cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects experienced inflamatory activity and negative immunological responses ...

Vector Targeting for Therapeutic Gene Delivery

Vector Targeting for Therapeutic Gene Delivery
  • Author : David T. Curiel,Joanne T. Douglas
  • Publisher : Wiley-Liss
  • Release Date : 2002-08-26
  • Total pages : 710
  • ISBN : 0128005106
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Summary : This book presents the most recent advances in target definition technology and provides a detailed overview on the rational design of targeted vectors for gene therapy. This unique reference integrates all of the allied sciences relevant to vector targeting by providing a theoretical framework for advanced vector design....

Construction and Evaluation of High capacity Adenoviral Vectors for Gene Therapy Applications

Construction and Evaluation of High capacity Adenoviral Vectors for Gene Therapy Applications
  • Author : Maurizio Buggio
  • Publisher : Unknown
  • Release Date : 2011
  • Total pages : 212
  • ISBN : 0128005106
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Summary : Download or read online Construction and Evaluation of High capacity Adenoviral Vectors for Gene Therapy Applications written by Maurizio Buggio, published by which was released on 2011. Get Construction and Evaluation of High capacity Adenoviral Vectors for Gene Therapy Applications Books now! Available in PDF, ePub and Kindle....

Improving Adenovirus Vectors for Gene Therapy

Improving Adenovirus Vectors for Gene Therapy
  • Author : Steven James Riley
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 0128005106
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Summary : Download or read online Improving Adenovirus Vectors for Gene Therapy written by Steven James Riley, published by which was released on 1998. Get Improving Adenovirus Vectors for Gene Therapy Books now! Available in PDF, ePub and Kindle....

Viral Gene Therapy

Viral Gene Therapy
  • Author : Ke Xu
  • Publisher : IntechOpen
  • Release Date : 2011-07-20
  • Total pages : 464
  • ISBN : 0128005106
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Summary : The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign ...

Construction of Safer and Controllable Adenoviral Vectors for Gene Therapy and for Measuring Trans effects on Resident Genes

Construction of Safer and Controllable Adenoviral Vectors for Gene Therapy and for Measuring Trans effects on Resident Genes
  • Author : Stefano Brenz Verca
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 94
  • ISBN : 0128005106
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Summary : Download or read online Construction of Safer and Controllable Adenoviral Vectors for Gene Therapy and for Measuring Trans effects on Resident Genes written by Stefano Brenz Verca, published by which was released on 1997. Get Construction of Safer and Controllable Adenoviral Vectors for Gene Therapy and for Measuring Trans effects on ...

Gene Therapy and Cancer Research Progress

Gene Therapy and Cancer Research Progress
  • Author : Jessica L. Lewis
  • Publisher : Nova Publishers
  • Release Date : 2008
  • Total pages : 225
  • ISBN : 0128005106
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Summary : Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority ...

Adenovirus vector rescue production and analysis

Adenovirus vector rescue  production and analysis
  • Author : Simon Schwörer
  • Publisher : GRIN Verlag
  • Release Date : 2012-05-23
  • Total pages : 14
  • ISBN : 0128005106
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Summary : Internship Report from the year 2012 in the subject Medicine - Other, grade: 1,3, University of Ulm (Abteilung für Gentherapie), language: English, abstract: Adenoviral vectors are among the oldest and most widely used vectors for gene therapy applications. Compared to other types of vectors, they have many advantages, including the extensive ...

Gene Delivery to Mammalian Cells

Gene Delivery to Mammalian Cells
  • Author : William C. Heiser
  • Publisher : Springer Science & Business Media
  • Release Date : 2004
  • Total pages : 592
  • ISBN : 0128005106
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Summary : Whether to assess the function of new genes identified from the Human Genome Project or to apply gene therapy successfully, it is often necessary to deliver genes to specific cells. In Gene Delivery to Mammalian Cells, highly experienced researchers describe in great detail methods that have proven most useful in ...

Approaches to Blocking the Immune Response to Gene Transfer with Viral Vectors

Approaches to Blocking the Immune Response to Gene Transfer with Viral Vectors
  • Author : Katherine High,Roland W. Herzog,Hildegund C. Ertl
  • Publisher : Frontiers E-books
  • Release Date : 2022-05-21
  • Total pages : 212
  • ISBN : 0128005106
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Summary : Viral vectors are superior tools for gene therapy and as a genetic vaccine platform because viruses have evolved to efficiently infect and transfer their genomes to cells. Several impressive successes in viral vector-based gene therapies have been reported in humans, including restoration of vision in patients with Leber’s congenital ...