A Comprehensive Guide to Toxicology in Nonclinical Drug Development

Written By Ali S. Faqi
A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Publsiher : Academic Press
  • Release : 03 November 2016
  • ISBN : 0128036214
  • Pages : 986 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi which was release on 03 November 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2016-11-03
  • Total pages : 986
  • ISBN : 0128036214
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Summary : A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem ...

A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2012-11-16
  • Total pages : 885
  • ISBN : 0128036214
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Summary : A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide ...

Current Topics in Nonclinical Drug Development

Current Topics in Nonclinical Drug Development
  • Author : Pritam S. Sahota,Philip Bentley,Zbigniew Wojcinski
  • Publisher : CRC Press
  • Release Date : 2020-12-23
  • Total pages : 318
  • ISBN : 0128036214
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Summary : The inaugural volume in the Current Topics in Nonclinical Drug Development Series explores the critical issues and current topics in nonclinical drug development. This first volume covers individual topics and strategies in drug development from compound characterization to drug registration. Written by a variety of experts in the field, recent ...

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-13
  • Total pages : 716
  • ISBN : 0128036214
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Summary : The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, ...

Essentials of Laboratory Animal Science Principles and Practices

Essentials of Laboratory Animal Science  Principles and Practices
  • Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
  • Publisher : Springer Nature
  • Release Date : 2021-07-23
  • Total pages : 806
  • ISBN : 0128036214
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Summary : This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used ...

Preclinical Development Handbook

Preclinical Development Handbook
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2008-03-21
  • Total pages : 1080
  • ISBN : 0128036214
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Summary : A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use ...

Drug Discovery and Development Third Edition

Drug Discovery and Development  Third Edition
  • Author : James J. O'Donnell,John Somberg,Vincent Idemyor,James T. O'Donnell
  • Publisher : CRC Press
  • Release Date : 2019-12-13
  • Total pages : 668
  • ISBN : 0128036214
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Summary : Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of ...

Botanical Drug Products

Botanical Drug Products
  • Author : Jayant N. Lokhande,Yashwant V. Pathak
  • Publisher : CRC Press
  • Release Date : 2018-11-21
  • Total pages : 274
  • ISBN : 0128036214
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Summary : Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the ...

Pharmacoepidemiology and Pharmacovigilance

Pharmacoepidemiology and Pharmacovigilance
  • Author : Sabrina Nour,Gilles Plourde
  • Publisher : Academic Press
  • Release Date : 2018-10-17
  • Total pages : 144
  • ISBN : 0128036214
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Summary : Pharmacoepidemiology and Pharmacovigilance: Synergistic Tools to Better Investigate Drug Safety examines the role of pharmacoepidemiologic studies in drug development and its use as a prevention tool in pharmacovigilance activities. The book introduces the various epidemiologic tools and study designs commonly used for the surveillance of drug-related adverse effects and reviews ...

Drug Safety in Developing Countries

Drug Safety in Developing Countries
  • Author : Yaser Mohammed Al-Worafi
  • Publisher : Academic Press
  • Release Date : 2020-06-03
  • Total pages : 686
  • ISBN : 0128036214
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Summary : Drug Safety in Developing Countries: Achievements and Challenges provides comprehensive information on drug safety issues in developing countries. Drug safety practice in developing countries varies substantially from country to country. This can lead to a rise in adverse reactions and a lack of reporting can exasperate the situation and lead ...

Nonclinical Drug Administration

Nonclinical Drug Administration
  • Author : Shayne C. Gad,Charles B. Spainhour
  • Publisher : CRC Press
  • Release Date : 2017-08-14
  • Total pages : 420
  • ISBN : 0128036214
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Summary : If we will ever achieve Paul Ehrlich’s "magic bullet," that is, a molecule which goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body, the practice of safety assessment will have to change. Nonclinical Drug Administration: Formulations, ...

Toxicologic Pathology for Non Pathologists

Toxicologic Pathology for Non Pathologists
  • Author : Thomas J. Steinbach,Daniel J. Patrick,Mary Ellen Cosenza
  • Publisher : Springer Nature
  • Release Date : 2019-10-31
  • Total pages : 919
  • ISBN : 0128036214
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Summary : This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help ...

Eco Friendly Biobased Products Used in Microbial Diseases

Eco Friendly Biobased Products Used in Microbial Diseases
  • Author : Mahendra Rai,Chistiane M. Feitosa
  • Publisher : CRC Press
  • Release Date : 2022-06-09
  • Total pages : 358
  • ISBN : 0128036214
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Summary : There are alarming reports of new and emerging microbial diseases. The recent emergence of COVID-19 is a burning example that has attracted global attention. Not only this, the development of multidrug resistance in microbes is frightening and thus the available antibiotics have been ineffective. Considering these facts, there is a ...

Human Drug Metabolism

Human Drug Metabolism
  • Author : Michael D. Coleman
  • Publisher : John Wiley & Sons
  • Release Date : 2020-02-19
  • Total pages : 680
  • ISBN : 0128036214
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Summary : Provides a timely update to a key textbook on human drug metabolism The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines ...

Biomedical Product and Materials Evaluation

Biomedical Product and Materials Evaluation
  • Author : P.V. Mohanan
  • Publisher : Woodhead Publishing
  • Release Date : 2022-01-22
  • Total pages : 806
  • ISBN : 0128036214
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Summary : Biomedical Product and Materials Evaluation: Standards and Ethics provides a much-needed overview of the procedures, issues, standards and ethical issues in the early development of biomedical products. The book covers a range of key biomedical products, from 3D printed organs and blood derived products, to stem calls and decellularized tissue ...